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Quinapril hydrochloride - Generic Drug Details
What are the generic sources for quinapril hydrochloride and what is the scope of freedom to operate?
Quinapril hydrochloride
is the generic ingredient in two branded drugs marketed by Pfizer Pharms, Actavis Elizabeth, Actavis Labs Fl Inc, Ani Pharms Inc, Apotex Inc, Aurobindo Pharma Ltd, Invagen Pharms, Lupin, Mylan, Prinston Inc, Sun Pharm Inds Ltd, and Yaopharma Co Ltd, and is included in fourteen NDAs. Additional information is available in the individual branded drug profile pages.There are eleven drug master file entries for quinapril hydrochloride. Thirteen suppliers are listed for this compound. There is one tentative approval for this compound.
Summary for quinapril hydrochloride
| US Patents: | 0 |
| Tradenames: | 2 |
| Applicants: | 12 |
| NDAs: | 14 |
| Drug Master File Entries: | 11 |
| Suppliers / Packagers: | 13 |
| Bulk Api Vendors: | 61 |
| Clinical Trials: | 26 |
| Patent Applications: | 2,443 |
| Formulation / Manufacturing: | see details |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for quinapril hydrochloride |
| DailyMed Link: | quinapril hydrochloride at DailyMed |
Recent Clinical Trials for quinapril hydrochloride
Identify potential brand extensions & 505(b)(2) entrants
| Sponsor | Phase |
|---|---|
| University of Nebraska | Phase 4 |
| Pfizer | N/A |
| St Thomas' Hospital, London | Phase 3 |
Recent Litigation for quinapril hydrochloride
Identify potential future generic entrants
District Court Litigation
| Case Name | Date |
|---|---|
| Apotex, Inc. v. UCB, Inc. | 2012-04-20 |
| Apotex, Inc. v. Mylan Pharmaceuticals, Inc. | 2012-04-20 |
| Fleetwood Enterprises, Inc. | 2009-03-10 |
Generic filers with tentative approvals for QUINAPRIL HYDROCHLORIDE
| Applicant | Application No. | Strength | Dosage Form |
| See Pricing | See Pricing | EQ 40MG BASE | TABLET;ORAL |
| See Pricing | See Pricing | EQ 20MG BASE | TABLET;ORAL |
| See Pricing | See Pricing | EQ 10MG BASE | TABLET;ORAL |
The 'tentative' approval signifies that the product meets all FDA standards for marketing, and, but for the patents / regulatory protections, it would approved.
Pharmacology for quinapril hydrochloride
| Drug Class | Angiotensin Converting Enzyme Inhibitor |
| Mechanism of Action | Angiotensin-converting Enzyme Inhibitors |
Synonyms for quinapril hydrochloride
| (3S-(2(R*(R*)),3R*))-2-(2-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID MONOHYDROCHLORIDE |
| (3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride |
| (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Hydrochloride |
| (3S)-2-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride |
| (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride |
| (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride |
| (3S)-2-[(2S)-2-{[(2S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YL]AMINO}PROPANOYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE |
| (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride |
| (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride |
| (S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride |
| (S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan- |
| (S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride |
| (S)-2-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride |
| (S)-2-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid 1-Ethyl Ester Hydrochloride |
| [3S-[2[R*(R*)], 3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride |
| 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid |
| 2-ylamino)propanoyl)-1,2,3,4- |
| 3-isoquinolineacrboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, (3S-(2(R*(R*)),3R*))- |
| 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (3S-(2(R*(R*)),3R*))- |
| 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*)) |
| 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))- |
| 3-isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-p |
| 33067B3N2M |
| 586Q558 |
| 82586-55-8 |
| AB07655 |
| AB2000675 |
| AC-1655 |
| AC1L1HXI |
| Accupril |
| Accupril (TN) |
| Accuprin |
| Accupro |
| Accupron |
| Accuretic |
| Acequin |
| Acuitel |
| Acuprel |
| AKOS015888532 |
| AN-14706 |
| AS-14026 |
| Asig |
| BC206223 |
| C07340 |
| C25H30N2O5.HCl |
| CAS-82586-55-8 |
| CCG-39543 |
| CHEBI:8714 |
| CHEMBL1201011 |
| CI 906 |
| CI-906 |
| CI-906 (CN-109452) |
| CI906 |
| Conan |
| Continucor |
| CPD000499582 |
| CS-2591 |
| D00459 |
| DSSTox_CID_1221 |
| DSSTox_GSID_21221 |
| DSSTox_RID_76019 |
| DTXSID3021221 |
| Ectren |
| Hemokvin |
| HMS1922C15 |
| HSDB 7046 |
| HY-B0477 |
| IBBLRJGOOANPTQ-JKVLGAQCSA-N |
| Korec |
| Koretic |
| Lidaltrin |
| LS-85471 |
| MCULE-2623123657 |
| MFCD00889215 |
| MLS001076683 |
| MolPort-003-666-434 |
| monohydrochloride,(3s-(2(r*(r*)),3r*))-henylpropyl)amino)-1-oxopropyl) |
| NC00722 |
| NCGC00094997-01 |
| NCGC00167962-06 |
| NCGC00257944-01 |
| NE45380 |
| NSC-758222 |
| NSC758222 |
| PD 109452-2 |
| PD-109,452-2 |
| PD-109522 |
| Pharmakon1600-01503076 |
| Quinapril hydrochloride |
| Quinapril (hydrochloride) |
| Quinapril for peak identification, European Pharmacopoeia (EP) Reference Standard |
| Quinapril for system suitability, European Pharmacopoeia (EP) Reference Standard |
| QUINAPRIL HCL |
| Quinapril Hydrochloride ,(S) |
| Quinapril hydrochloride (Accupril) |
| Quinapril hydrochloride (JP17/USP) |
| Quinapril hydrochloride [USAN:USP] |
| Quinapril hydrochloride [USAN] |
| quinapril hydrochloride hydrochloride |
| Quinapril hydrochloride, >=98% (HPLC), solid |
| Quinapril hydrochloride, European Pharmacopoeia (EP) Reference Standard |
| Quinapril Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
| Quinapril hydrochloride, United States Pharmacopeia (USP) Reference Standard |
| Quinapril hydrochloride; |
| Quinapril N-Oxide |
| Quinapril.HCl |
| Quinazil |
| s2581 |
| SAM002589972 |
| SC-17215 |
| SCHEMBL41404 |
| SMR000499582 |
| SPECTRUM1503076 |
| SR-01000765404 |
| SR-01000765404-2 |
| SW199393-2 |
| tetrahydroisoquinoline-3-carboxylic |
| Tox21_111381 |
| Tox21_111381_1 |
| Tox21_200390 |
| UNII-33067B3N2M |
US Patents and Regulatory Information for quinapril hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Invagen Pharms | QUINAPRIL HYDROCHLORIDE | quinapril hydrochloride | TABLET;ORAL | 078457-003 | Aug 24, 2007 | AB | RX | No | No | See Pricing | See Pricing | See Pricing | |||
| Pfizer Pharms | ACCUPRIL | quinapril hydrochloride | TABLET;ORAL | 019885-003 | Nov 19, 1991 | AB | RX | Yes | No | See Pricing | See Pricing | See Pricing | |||
| Prinston Inc | QUINAPRIL HYDROCHLORIDE | quinapril hydrochloride | TABLET;ORAL | 205823-001 | Sep 15, 2016 | AB | RX | No | No | See Pricing | See Pricing | See Pricing | |||
| Ani Pharms Inc | QUINAPRIL HYDROCHLORIDE | quinapril hydrochloride | TABLET;ORAL | 075504-002 | Aug 24, 2007 | AB | RX | No | No | See Pricing | See Pricing | See Pricing | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Exclusivity Expiration |
Expired US Patents for quinapril hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Pfizer Pharms | ACCUPRIL | quinapril hydrochloride | TABLET;ORAL | 019885-002 | Nov 19, 1991 | See Pricing | See Pricing |
| Pfizer Pharms | ACCUPRIL | quinapril hydrochloride | TABLET;ORAL | 019885-004 | Nov 19, 1991 | See Pricing | See Pricing |
| Pfizer Pharms | ACCUPRIL | quinapril hydrochloride | TABLET;ORAL | 019885-004 | Nov 19, 1991 | See Pricing | See Pricing |
| Pfizer Pharms | ACCUPRIL | quinapril hydrochloride | TABLET;ORAL | 019885-001 | Nov 19, 1991 | See Pricing | See Pricing |
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >Patent No. | >Patent Expiration |
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Major Patent Expirations 2019 - 2020
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ISSN: 2162-2639
Privacy and Cookies
Terms & Conditions
Site Map
DrugPatentWatch Alternatives
Major Patent Expirations 2019 - 2020
NCE-1 Generic Application Dates 2019 - 2020
Preferred Citation:
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2019, www.DrugPatentWatch.com.