Isopropyl alcohol - Generic Drug Details

What are the generic sources for isopropyl alcohol and what is the scope of patent protection?

Isopropyl alcohol is the generic ingredient in one branded drug marketed by Zurex Pharma and is included in one NDA. There are seven patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Isopropyl alcohol has sixty-five patent family members in twenty-two countries.

There is one drug master file entry for isopropyl alcohol.

Summary for isopropyl alcohol

International Patents:	65
US Patents:	7
Tradenames:	1
Applicants:	1
NDAs:	1
Drug Master File Entries:	1
Raw Ingredient (Bulk) Api Vendors:	384
Clinical Trials:	54
Patent Applications:	5,166
What excipients (inactive ingredients) are in isopropyl alcohol?	isopropyl alcohol excipients list
DailyMed Link:	isopropyl alcohol at DailyMed

DrugPatentWatch^® Estimated Loss of Exclusivity (LOE) Date for isopropyl alcohol

Dosage:

SOLUTION;TOPICAL

^*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

Recent Clinical Trials for isopropyl alcohol

Identify potential brand extensions & 505(b)(2) entrants

Sponsor	Phase
Yaneve Fonge	Phase 4
University of Calgary	Phase 2
State University of New York at Buffalo	Phase 2/Phase 3

See all isopropyl alcohol clinical trials

US Patents and Regulatory Information for isopropyl alcohol

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes			Y
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes			Y
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes			Y
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019		OTC	Yes	Yes			Y

Expired US Patents for isopropyl alcohol

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019
Zurex Pharma	ZURAGARD	isopropyl alcohol	SOLUTION;TOPICAL	210872-001	Apr 26, 2019

International Patents for isopropyl alcohol

Country	Patent Number	Title	Estimated Expiration
Russian Federation	2519038	АНТИМИКРОБНЫЕ КОМПОЗИЦИИ И СПОСОБЫ ПРИМЕНЕНИЯ (ANTIMICROBIAL COMPOSITIONS AND METHODS OF USING THEM)
Austria	E453415
China	105377323	MEDICAL SKIN APPLICATOR APPARATUS
Russian Federation	2007133649	РАСТВОР ЗАМКА КАТЕТОРА, СОДЕРЖАЩИЙ ЦИТРАТ И ПАРАБЕН
Australia	2019201266	Medical skin applicator apparatus
European Patent Office	1688154	Solution de verrou pour cathéter contenant un citrate et un parabène (A catheter lock solution comprising citrate and a paraben)

Supplementary Protection Certificates for isopropyl alcohol

Patent Number	Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
1448186	C300550	Netherlands		PRODUCT NAME: MENGSEL VAN CATECHOLEN GEISOLEERD UIT EEN EXTRACT VAN GROENE THEE, CAMELLIA SINENSIS, L. O. KUNTZE MET ISOPROPYLMYRISTAAT; NATL. REGISTRATION NO/DATE: RVG 110904 20120920; FIRST REGISTRATION: DE 73486.00.00 20090831
1920764	2012/033	Ireland		PRODUCT NAME: TRAVOPROST (ALSO CALLED FLUPROSTENOL ISOPROPYL ESTER); NAT REGISTRATION NO/DATE: EU/1/01/199/001-002 20011129; FIRST REGISTRATION NO/DATE: EU/1/01/199/001-002 20011129; PAEDIATRIC INVESTIGATION PLAN: P/0298/2013 PROCEEDINGS UNDER SECTION 37 OF THE PATENTS ACT, 1992 RESTORATION ORDER DATED 12TH JANUARY 2016, WAS MADE RESTORING THE PATENT MENTIONED BELOW S85583 PAUL DOYLE A RE-USABLE BAG SYSTEM RESTORATION ORDERS DATED 16TH FEBRUARY 2016, WERE MADE RESTORING THE PATENTS MENTIONED BELOW S86133 MERVYN GREENE MULTI PURPOSE TANK STAND WITH COMPLEX LOCKING MECHANISM 86119 MPC GREEN LIMITED ANEW BIN
0289349	SPC/GB04/007	United Kingdom		PRODUCT NAME: ISOPROPYL(+)-(Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-(3-OXODECYL)CYCLOPENTYL)-5-HEPTENOATE; REGISTERED: CH 55634 01 20010329; UK PL00101/0667 20031112
2203462	2014029	Norway		PRODUCT NAME: SOFOSBUVIR. (S)-ISOPROPYL 2-; NAT. REG. NO/DATE: EU/1/13/894 20140116; FIRST REG. NO/DATE: (001-002) 20140117
1448186	29/2010	Austria		PRODUCT NAME: "(-)-EPIGALLOCATECHIN GALLAT MIT ISOPROPYLMYRISTAT"; NAT. REGISTRATION NO/DATE: 1-29000 20100217; FIRST REGISTRATION: DE 73486.00.00 (MITTEILUNG) 20090908
2447254	2018015	Norway		PRODUCT NAME: 2-4-(N-(5,6-DIFENYLPYRAZIN-2- YL)-N- ISOPROPYLAMINO)BUTYLOKSY-N-; REG. NO/DATE: EU/1/15/1083 20160530

Isopropyl Alcohol Market Dynamics and Financial Trajectory

Market Size and Growth

The global isopropyl alcohol market is poised for significant growth in the coming years. As of 2024, the market size is estimated to be around USD 3.18 billion and is expected to reach USD 3.97 billion by 2029, growing at a CAGR of 4.54% during the forecast period[1].

By 2032, the market is projected to expand further, with estimates suggesting it will be worth around USD 5.7 billion to USD 5.9 billion, driven by a CAGR of 6.90% to 8.1% from 2023 to 2032[3][4].

Impact of COVID-19

The COVID-19 pandemic had a mixed impact on the isopropyl alcohol market. Initially, demand declined due to disruptions in the packaging and agriculture sectors. However, the medical industry's increased demand for isopropyl alcohol as a disinfectant and antiseptic helped the market register a slight growth rate during the pandemic[1].

Key Drivers of Market Growth

Several factors are driving the growth of the isopropyl alcohol market:

• Pharmaceutical and Healthcare Sectors: The expanding market for disinfectants and sanitizers, particularly in healthcare and pharmaceuticals, significantly drives the demand for isopropyl alcohol. Its use in hand sanitizers, disinfectants, and pharmaceutical products is a major growth driver[4].
• Personal Care and Cosmetics: Growing utilization in the personal care and cosmetics industry is another key factor. Isopropyl alcohol's high solvency characteristics make it a vital component in various personal care products[1][3].
• Industrial Applications: The chemical is widely used as a solvent, cleaning agent, and chemical intermediate in various industries such as paints, coatings, chemicals, and food and beverage. Increasing industrial applications are contributing to the market's growth[3].

Regional Market Dynamics

• Asia-Pacific: This region is expected to dominate the isopropyl alcohol market. The region saw significant price surges during the COVID-19 pandemic due to limited stocks and supply chain disruptions[2].
• North America: In North America, the market experienced fluctuations in 2024, with initial price decreases and inventory increases. However, the market stabilized as external deliveries and consumption patterns balanced out. The region is expected to see new production facilities coming online in 2024, albeit at a restrained pace[5].
• Europe: The European market faced challenges due to supply chain disruptions, including force majeure at production facilities and logistical bottlenecks, which drove up prices and created a bullish market trend[2].

Price Trends and Forecast

The price trends for isopropyl alcohol have been volatile, influenced by various factors:

• Raw Material Costs: Fluctuations in the costs of raw materials, particularly propylene, have significantly impacted the pricing dynamics of isopropyl alcohol. For instance, in January 2024, the surge in raw material costs led manufacturers to absorb increased costs initially to maintain competitiveness[5].
• Supply Chain Disruptions: Logistical challenges, such as train driver strikes in Germany and maritime shipment disruptions, have exerted upward pressure on prices. In contrast, robust supply and inventory buffers have led to price reductions in some regions[2][5].
• Regional Imbalances: The market dynamics are dependent on regional industrial outlooks and export-import balances, leading to regional imbalances in pricing patterns[2].

Analyst Insights

According to analysts, the price trend of isopropyl alcohol is expected to face challenges such as trade disruptions, uneven pricing patterns of feedstock chemicals, and rises in crude oil prices in the coming quarters of 2024. However, the overall outlook suggests that the market will stabilize as supply and demand dynamics balance out[2].

Challenges and Opportunities

• Substitute Products: The availability of substitute products for isopropyl alcohol remains a major concern for the market. This could potentially reduce demand and impact market growth[1].
• Innovation in Bio-Based IPA: Innovation in bio-based isopropyl alcohol is likely to create opportunities for the market in the coming years, offering a more sustainable alternative[1].

Key Applications

Isopropyl alcohol is a versatile solvent with various applications:

• Medical and Pharmaceutical: It is used as an antiseptic and astringent, and in the production of hand sanitizers and disinfectants[3][4].
• Personal Care and Cosmetics: It is used in the production of various personal care products due to its high solvency characteristics[1][3].
• Industrial Solvent: It is used as a solvent, cleaning agent, and chemical intermediate in industries such as paints, coatings, and chemicals[3].

Market Stability and Future Outlook

The market is expected to stabilize as new production facilities come online and supply chain dynamics improve. However, external factors such as geopolitical events and fluctuations in raw material costs could influence the trajectory of isopropyl alcohol prices in the coming months.

"Isopropyl alcohol provides high solvency characteristics, making it one of the most important solvents in all end-use sectors. Due primarily to its disinfection qualities, the chemical is also a vital component utilized in several medical facilities, pharmaceutical products, and medical devices."[3]

Key Takeaways

• The global isopropyl alcohol market is expected to grow significantly, driven by demand from pharmaceutical, healthcare, and personal care sectors.
• Regional market dynamics are influenced by supply chain disruptions, raw material costs, and logistical challenges.
• Innovation in bio-based isopropyl alcohol presents future opportunities.
• The market faces challenges from substitute products but is stabilized by robust supply and balanced demand.

FAQs

Q: What is the projected market size of isopropyl alcohol by 2032? A: The global isopropyl alcohol market is expected to be worth around USD 5.7 billion to USD 5.9 billion by 2032[3][4].

Q: How did the COVID-19 pandemic impact the isopropyl alcohol market? A: The pandemic initially reduced demand due to disruptions in packaging and agriculture sectors but saw a slight growth rate due to increased demand from the medical industry[1].

Q: What are the key drivers of the isopropyl alcohol market growth? A: Key drivers include rising demand from pharmaceutical and healthcare sectors, growing utilization in personal care and cosmetics, and increasing industrial applications[1][3][4].

Q: Which region is expected to dominate the isopropyl alcohol market? A: The Asia-Pacific region is expected to dominate the market[1].

Q: What are the challenges facing the isopropyl alcohol market? A: The market faces challenges from the availability of substitute products and fluctuations in raw material costs, among other factors[1][2].

Sources

1. Mordor Intelligence - Isopropyl Alcohol (IPA) Market Size | Mordor Intelligence
2. Procurement Resource - Isopropyl Alcohol Price Trend and Forecast - Procurement Resource
3. Market.US - Isopropyl Alcohol Market Size, Share | CAGR of 6.90%
4. Allied Market Research - Isopropyl Alcohol Market Size, Share | Industry Growth Report, 2032
5. ChemAnalyst - As January Comes to a Close, Isopropyl Alcohol Stocks Rise Across North America

Last updated: 2024-12-18