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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
US Army
Argus Health
Healthtrust
Moodys
McKinsey
Daiichi Sankyo
McKesson
Fuji

Generated: July 15, 2018

DrugPatentWatch Database Preview

Ipratropium bromide - Generic Drug Details

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What are the generic sources for ipratropium bromide and what is the scope of ipratropium bromide freedom to operate?

Ipratropium bromide
is the generic ingredient in three branded drugs marketed by Boehringer Ingelheim, Actavis Mid Atlantic, Apotex Inc, Aurobindo Pharma Ltd, Bausch And Lomb Inc, Landela Pharm, Mylan Speciality Lp, Nephron, Pharmascience Inc, Ritedose Corp, Roxane, Sun Pharma Global, Teva Pharms Usa, Watson Labs, Bausch And Lomb, and West-ward Pharms Int, and is included in twenty-six NDAs. There are three patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Ipratropium bromide has fifty-nine patent family members in thirty-eight countries.

There are eight drug master file entries for ipratropium bromide. Twenty-two suppliers are listed for this compound.
Summary for ipratropium bromide
Pharmacology for ipratropium bromide
Drug ClassAnticholinergic
Mechanism of ActionCholinergic Antagonists
Medical Subject Heading (MeSH) Categories for ipratropium bromide
Synonyms for ipratropium bromide
(1R,5S)-3-((3-hydroxy-2-phenylpropanoyl)oxy)-8-isopropyl-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide
(1R,5S)-3-[(3-HYDROXY-2-PHENYLPROPANOYL)OXY]-8-ISOPROPYL-8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-8-IUM BROMIDE
(1S,3S,5R)-3-Tropyloxy-8-isopropyltropanium bromide
(3-Endo,8-anti)-3-((3-hydroxy-2-phenylpropanoyl)oxy)-8-isopropyl-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide
(3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
(8r)-3-alpha-Hydroxy-8-isopropyl-1-alpha-H,5-alpha-H-tropiumbromide-(+-)-tropate
(endo,Anti)-(1)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-isopropyl-8-methyl-8-azoniabicyclo(3.2.1)octane bromide
(endo,syn)-(+-)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
(endo,syn)-(+/-)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
(exo,Syn)-(1)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-isopropyl-8-methyl-8-azoniabicyclo(3.2.1)octane bromide
1-alpha-H,5-alpha-H-Tropanium, 3-alpha-hydroxy-8-isopropyl-, bromide, (+-)-tropate
22254-24-6
22254-36-0
24358-20-1
3-alpha-Hydroxy-8-isopropyl-1-alpha-H,5-alpha-H-tropanium bromide (+-)-tropate
3alpha-hydroxy-8-isopropyl-1alphaH,5alphaH-tropanium bromide (+-)-tropate
3alpha-hydroxy-8-isopropyl-1alphaH,5alphaH-tropanium bromide (+/-)-tropate
58073-59-9
60205-81-4 (Parent)
60251-88-9
8-Azoniabicyclo(3.2.1)octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, endo-
8-Isopropylnoratropine methobromide
AK110411
AK277771
AKOS015895324
AKOS016013651
AKOS027301349
AKOS030485952
ATEM
ATROPINE ISOPROPYLBROMIDE
Atrovent
Atrovent Hfa
BC677124
BDBM50021892
Bromure d'ipratropium
Bromure d'ipratropium [INN-French]
Bromuro de ipratropio
Bromuro de ipratropio [INN-Spanish]
C20H30BrNO3
CHEBI:46659
CHEMBL1464005
DB00332
DR002476
DTXSID60858923
EINECS 244-873-8
EINECS 246-197-9
EINECS 261-098-0
EINECS 262-128-5
HE326281
HMS2234J05
Ipatropium Bromide
Ipratropii bromidum
Ipratropii bromidum [INN-Latin]
Ipratropium Bromide (anhydrous)
Ipratropium bromide [INN]
Ipratropium bromide anhydrous
Ipratropium bromide monohydrate
Ipratropiumbromid
Ipratropiumbromid [German]
Ipratropiumbromide
Itrop
MFCD00069291
MLS000069557
MolPort-006-069-092
MolPort-027-946-829
MolPort-035-924-120
N-Isopropylnoratropinium bromomethylate
N-Isopropylnortropine tropate methobromide
Opera_ID_1621
Prestwick_279
REGID_for_CID_657308
SC-14062
Sch 1000
SCHEMBL107906
SCHEMBL16762661
SCHEMBL3852
SCHEMBL3854
SMR000058764
ST51052817
UNII-VJV4X1P2Z1

US Patents and Regulatory Information for ipratropium bromide

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Roxane IPRATROPIUM BROMIDE ipratropium bromide SOLUTION;INHALATION 075867-001 Jul 22, 2002 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Nephron IPRATROPIUM BROMIDE ipratropium bromide SOLUTION;INHALATION 075562-001 Sep 27, 2001 AN RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Boehringer Ingelheim ATROVENT ipratropium bromide SPRAY, METERED;NASAL 020394-001 Oct 20, 1995 DISCN Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Boehringer Ingelheim ATROVENT HFA ipratropium bromide AEROSOL, METERED;INHALATION 021527-001 Nov 27, 2004 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for ipratropium bromide

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Boehringer Ingelheim ATROVENT ipratropium bromide AEROSOL, METERED;INHALATION 019085-001 Dec 29, 1986 ➤ Sign Up ➤ Sign Up
Boehringer Ingelheim ATROVENT HFA ipratropium bromide AEROSOL, METERED;INHALATION 021527-001 Nov 27, 2004 ➤ Sign Up ➤ Sign Up
Boehringer Ingelheim ATROVENT HFA ipratropium bromide AEROSOL, METERED;INHALATION 021527-001 Nov 27, 2004 ➤ Sign Up ➤ Sign Up
Boehringer Ingelheim ATROVENT ipratropium bromide SPRAY, METERED;NASAL 020394-001 Oct 20, 1995 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Harvard Business School
Express Scripts
Teva
Chubb
Merck
US Army
Chinese Patent Office
US Department of Justice

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