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Generated: November 15, 2018

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Iloprost - Generic Drug Details

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What are the generic drug sources for iloprost and what is the scope of iloprost freedom to operate?

Iloprost is the generic ingredient in one branded drug marketed by Actelion Pharms Ltd and is included in one NDA. Additional information is available in the individual branded drug profile pages.

There are four drug master file entries for iloprost. One supplier is listed for this compound.

Pharmacology for iloprost
Ingredient-typeProstaglandins I
Drug ClassProstacycline
Medical Subject Heading (MeSH) Categories for iloprost
Synonyms for iloprost
(16R,S)-Methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I(sub 2)
(16R,S)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I2
(1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane
(1S,2R,3R,5S)-7-[(E)-4-carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyne-1-enyl]-3-hydroxybicyclo[3.3.0]octane
(5E)-5-((3aS,4R,5R,6aS)-5-Hydroxy-4-((1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid
(5e)-5-[(3as,4r,5r,6as)-5-Hydroxy-4-[(1e,3s,4r)-3-Hydroxy-4-Methyloct-1-En-6-Yn-1-Yl]hexahydropentalen-2(1h)-Ylidene]pentanoic Acid
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyl-oct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid
(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoic acid
(5E)-5-[(3aS,5R,6aS)-4-[(E,3S)-4-methyl-3-oxidanyl-oct-1-en-6-ynyl]-5-oxidanyl-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(5E)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid
(5E)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyl-oct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(5E)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(5Z)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(E,3R)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric acid
(E)-5-(3aS,4R,5R,6aS)-5-Hydroxy-4((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-inyl)perhydropentalen-2-yliden)valeriansaeure
(Z)-5-((3aS,4R,5R,6aS)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid
[3H]-Iloprost
1212AH
16(R)-Iloprost
5-((3aS,5R,6aS,E)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid
5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid
5-[(2Z,3AS,5R,6AS)-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-METHYLOCT-1-EN-6-YN-1-YL]-HEXAHYDRO-1H-PENTALEN-2-YLIDENE]PENTANOIC ACID
5-[[(2E,3aS,4R,5R,6aS)-Octahydro-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyl-1-octene-6-ynyl]pentalene]-2-ylidene]pentanoic acid
6,9.alpha.-Methylene-11.alpha.,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
73873-87-7
74843-13-3
78919-13-8
A839531
AC-6105
AHG2128QW6
AK310881
AKOS024456922
AKOS025402197
AN-10394
AN-36592
B6933
BAY Q6256
BAY-q-6256
BC682483
BDBM23954
BRD-A45664787-001-01-4
BRD-A45664787-001-02-2
CAS-78919-13-8
CHEBI:63916
CHEMBL494
Ciloprost
CS-5586
CTK8G0274
D05ZTH
DB01088
DR001907
DSSTox_CID_21046
DSSTox_GSID_41046
DSSTox_RID_79616
DTXSID2041046
E-1030
Endoprost
GTPL1895
HIFJCPQKFCZDDL-ACWOEMLNSA-N
HIFJCPQKFCZDDL-JYTNZNGZSA-N
HMS3650E08
HY-A0096
IL2
Ilomedin
Ilomedine
Iloprost (INN)
Iloprost (USAN/INN)
Iloprost [BAN:INN]
Iloprost [USAN:INN:BAN]
Iloprost R-isomer
Iloprost, >=98% (HPLC)
Iloprostum
Iloprostum [Latin]
J-502615
K395
KS-00001F60
LP011661
MolPort-023-276-312
MolPort-039-138-876
NCGC00181784-01
OR107112
OR335390
Pentanoic acid, 5-((3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-((1E,3S,4R)-3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-, (5E)-
Pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-
Pentanoic acid,5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-,(5E)-
RP17693
SCHEMBL13386495
SCHEMBL15955636
SCHEMBL4357
SCHEMBL532499
SCHEMBL6083382
SH-401
SR-01000946274
SR-01000946274-1
SR-05000001498
SR-05000001498-1
SR-05000001498-2
Tox21_113586
UNII-AHG2128QW6
UNII-JED5K35YGL component HIFJCPQKFCZDDL-GBSCXWAGSA-N
Ventavis
Ventavis (TN)
ZINC3784120
ZK 00036374
ZK 36374
ZK-00036374
ZK-36374
ZK-363775
ZK36374

US Patents and Regulatory Information for iloprost

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Actelion Pharms Ltd VENTAVIS iloprost SOLUTION;INHALATION 021779-001 Dec 29, 2004 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Actelion Pharms Ltd VENTAVIS iloprost SOLUTION;INHALATION 021779-003 Aug 7, 2009 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Actelion Pharms Ltd VENTAVIS iloprost SOLUTION;INHALATION 021779-002 Dec 8, 2005 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Baxter
Federal Trade Commission
Moodys
Argus Health
UBS
QuintilesIMS
Merck
McKinsey

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