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Generated: June 24, 2019

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Calcipotriene - Generic Drug Details

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What are the generic drug sources for calcipotriene and what is the scope of calcipotriene patent protection?

Calcipotriene is the generic ingredient in three branded drugs marketed by Mayne Pharma, Glenmark Pharms, Tolmar, Leo Pharma As, Glenmark Pharms Inc, Acp Nimble, Fougera Pharms, Hi Tech Pharma, Novel Labs Inc, and Leo Pharm, and is included in twelve NDAs. There are two patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

Calcipotriene has twenty-six patent family members in twelve countries.

There are twelve drug master file entries for calcipotriene. Fourteen suppliers are listed for this compound.

Pharmacology for calcipotriene
Synonyms for calcipotriene
(1?,3?,5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
(1|A,3|A,5E,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,1R)-4-cyclopropyl-4-hydroxy-1-methyl-but-2-enyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylenecyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-oxidanyl-pent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol
(1R,3S,Z)-5-(2-((1R,7aR,E)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
(1S,3R,5Z,7E,14beta,17alpha,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol
(1S,3R,5Z,7E,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol
(1S,3S,5E)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
(1S,5Z,7Z,17ALPHA,22E)-24-CYCLOPROPYL-9,10-SECOCHOLA-5,7,10,22-TETRAENE-1,3,24-TRIOL
(1S,5Z,7Z,17ALPHA,22E)-24-CYCLOPROPYL-9,10-SECOCHOLA-5,7,10,22-TETRAENE-1,3,24-TRIOL; 1-ALPHA,24S-(OH)2-22-ENE-26,27-DEHYDROVITAMIN D3
(22E)-(24R)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydro-20-epivitamin D3 / (22E)-(24R)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydro-20-epicholecalciferol
(22E)-(24S)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydrovitamin D3 / (22E)-(24S)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydrocholecalciferol / Calcipotriol
(5E,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
(5E)-Calcipotriene
(5E)-Calcipotriol
(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol hydrate
(5Z,7E,22E)-(1S,3R,20S,24R)-26,27-cyclo-9,10-seco-5,7,10(19),22-cholestatetraene-1,3,24-triol
(5Z,7E,22E)-(1S,3R,24S)-26,27-cyclo-9,10-seco-5,7,10(19),22-cholestatetraene-1,3,24-triol
(5Z,7E,24S)-26,27-Cyclo-9,10-secocholesta-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
(5Z)-5-[(2Z)-2-[1-[(E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
1-ALPHA,24S-(OH)2-22-ENE-26,27-DEHYDROVITAMIN D3
1,24(OH)2-22-ene-24-cyclopropyl D3
1,3-Cyclohexanediol, 5-((2E)-2-((1R,3aS,7aR)-1-((1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-, (1S,3S,5E)-
112828-00-9
112965-21-6
113082-99-8
143NQ3779B
147657-22-5
1s19
24207-EP2275420A1
24207-EP2295055A2
24207-EP2295416A2
24207-EP2298748A2
24207-EP2298764A1
24207-EP2298765A1
24207-EP2305640A2
24207-EP2305642A2
24207-EP2308861A1
24207-EP2311453A1
24207-EP2314590A1
5,6-trans-Calcipotriol
828C009
9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1alpha,3beta,5E,7E,22E,24S)-
9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1alpha,3beta,5Z,7E,22E,24S)-
9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1alpha,3beta,5Z,7E,22E)-
9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-,(1-alpha,3-beta,5Z,7E,22E,24S)-
A802667
AB00698343-05
AC-4696
AC1NQZJ5
AC1NRC3V
AC1O455M
AC1O5L5S
AKOS005146500
AKOS015855239
AKOS024457248
AN-33413
BDBM50369964
BIDD:GT0282
BMS-181161
BRD-K56429665-001-03-9
Calcipotriene (USAN)
Calcipotriene [USAN]
CALCIPOTRIENE HYDRATE
Calcipotriol
Calcipotriol (JAN)
Calcipotriol [INN]
Calcipotriol hydrate
Calcipotriol, (5E)-
Calcipotriol, anhydrous
Calcipotriol, anhydrous impurity C [EP]
Calcipotriol, anhydrous specified impurity C [EP]
Calciptriol
Calciptriol, MC-903, Daivonex, Dovonex, Psorcutan
Calcitrene
CAS-112965-21-6
CCG-100949
CCRIS 7700
CHEBI:50749
CHEMBL1200666
CHEMBL1366876
CPD000466353
CS-0387
D01125
Daivonex
Davonex
DB02300
Divonex
Dovonex
Dovonex (TN)
DSSTox_CID_26648
DSSTox_GSID_46648
DSSTox_RID_81793
DTXSID0046648
Epitope ID:114242
FT-0082647
GTPL2778
HMS2051N11
HMS2089J08
HMS3269P03
HMS3713K08
HY-10001
LMST03020106
LMST03020107
LS-144707
LWQQLNNNIPYSNX-UROSTWAQSA-N
MC 903
MC-903
MC903
MFCD10567086
MLS000759467
MLS001424130
NC00199
NCGC00167465-01
NCGC00167465-02
NCGC00167837-01
O763
PRI 2201
PRI 2205
PRI-2205
Psorcutan
PubChem18810
PubChem19334
QRA3492A7Q
RTC-020913
SCHEMBL1131595
SCHEMBL13044528
SCHEMBL17430783
SCHEMBL2131847
SCHEMBL2853
SCHEMBL9360339
SMR000466353
Sorilux
SR-01000762910
SR-01000762910-3
SR-01000762910-4
STF-115469
TC-020913
Tox21_112469
Tox21_112469_1
U-0267
UNII-143NQ3779B
UNII-QRA3492A7Q
W-5148
ZINC3921872
ZINC77285174

US Patents and Regulatory Information for calcipotriene

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Glenmark Pharms Inc CALCIPOTRIENE calcipotriene OINTMENT;TOPICAL 090633-001 Mar 24, 2010 RX No Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Hi Tech Pharma CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 077579-001 Nov 19, 2009 AT RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Tolmar CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 077029-001 Nov 20, 2009 AT RX No Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Fougera Pharms CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 078305-001 May 6, 2008 AT RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Glenmark Pharms CALCIPOTRIENE calcipotriene CREAM;TOPICAL 205772-001 Jun 9, 2015 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Tolmar CALCIPOTRIENE calcipotriene CREAM;TOPICAL 200935-001 May 30, 2012 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Mayne Pharma SORILUX calcipotriene AEROSOL, FOAM;TOPICAL 022563-001 Oct 6, 2010 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for calcipotriene

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Leo Pharma As DOVONEX calcipotriene OINTMENT;TOPICAL 020273-001 Dec 29, 1993 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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International Patents for calcipotriene

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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Accenture
Boehringer Ingelheim
Healthtrust
Baxter
Cipla

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