Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Daiichi Sankyo
Healthtrust
Moodys
Farmers Insurance
Teva
Boehringer Ingelheim
Queensland Health
Colorcon

Generated: April 23, 2018

DrugPatentWatch Database Preview

DILTIAZEM HYDROCHLORIDE - Generic Drug Details

« Back to Dashboard

What are the generic drug sources for diltiazem hydrochloride and what is the scope of diltiazem hydrochloride freedom to operate?

Diltiazem hydrochloride
is the generic ingredient in eleven branded drugs marketed by Valeant Intl, Biovail, Actavis Labs Fl Inc, Allergan Sales Llc, Apotex, Actavis Elizabeth, Mylan, Nesher Pharms, Par Pharm, Sandoz, Sun Pharm Inds Ltd, Sun Pharma Global, Teva, Valeant Pharms North, Zydus Pharms Usa Inc, Apotex Inc, Biovail Labs Intl, Akorn Inc, Athenex Inc, Hikma Farmaceutica, Hospira, Intl Medication, Mylan Labs Ltd, Teva Pharms Usa, West-ward Pharms Int, Apothecon, Chartwell Molecules, Ivax Sub Teva Pharms, and Teva Pharms, and is included in forty-eight NDAs. There are two patents protecting this compound and two Paragraph IV challenges. Additional information is available in the individual branded drug profile pages.

Diltiazem hydrochloride has twenty-two patent family members in eleven countries.

There are twenty-six drug master file entries for diltiazem hydrochloride. Forty-four suppliers are listed for this compound.
Summary for DILTIAZEM HYDROCHLORIDE
Pharmacology for DILTIAZEM HYDROCHLORIDE
Synonyms for DILTIAZEM HYDROCHLORIDE
(+)-5-(2-(Dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester) monohydrochloride
(+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester monohydrochloride
(+)-cis-Diltiazem hydrochloride
(+)-cis-Diltiazem hydrochloride, >=99% (HPLC)
(2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
(2S-cis)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride
(2S-trans)-Diltiazem Hydrochloride
(2S,3S)-(+)-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride
(2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
(2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride
(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride
(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2H,3H-benzo[b]1,4 -thiazaperhydroepin-3-yl acetate, chloride
[(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate hydrochloride
[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride
1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-, monohydrochloride, cis-(+)-
1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis-
103532-26-9
2-[(2S,3S)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2H)-yl]-N,N-dimethylethanaminium chloride
286D225
33286-22-5
38411-61-9
AB2000340
AC-15189
AC1L1Y1J
AC1Q3C2G
AC1Q3EQ4
Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; hydrochloride
ACT02682
Adizem-CD
AK162004
AKOS015961992
Altiazem
Altiazem Retard
Altiazem RR
Anginyl
Angiotrofin
Angiotrofin Retard
Angitil
Angizem
Anzem
Apo-diltiazem
AS-13703
BC208729
Bi-Tildiem
BIM-0050315.0001
BNP-32762
Britiazim
Bruzem
C22H26N2O4S.HCl
Calcicard
Calnurs
Cardiazem
Cardil Retard
Cardizem (TN)
Cardizem CD
Cardizem LA
Cardizem Retard
Cardizem SR
Cardizem XL
Cardizem;Tiazac
Carex
Cartia XT
Cartia XT (TN)
Carzem
Carzen
CCG-220134
CCG-221631
CHEBI:645509
CHEMBL1697
Cirilen
Cirilen AP
cis-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one hydrochloride
cis-(1)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride
Citizen
Clarute
Coras
Corazet
CPD000058375
CRD 401
CRD-401
CS-2339
CTK8E8855
D 2521
D00616
D3662
Dazil
Deltazen
Diacor
Diatal
Dil-Sonaramia
Dilacor XR (TN)
Dilacor XR Extended Release Capsules
Diladel
Dilatam
Dilatam 120
Dilatame
Dilcard
Dilem
Dilfar
Dilgard
Dilicardin
Dilpral
Dilrene
Dilsal
Dilso
Dilt-CD (TN)
Dilt-XR
Diltahexal
Diltam
Diltan
Diltan SR
Diltelan
Dilthiazem hydrochloride
Dilthiazemhydrochloride
Diltia XT
Diltiasyn
Diltiazem (hydrochloride)
Diltiazem AWD
Diltiazem Basics
Diltiazem chloridrate
Diltiazem Eu Rho
Diltiazem for system suitability, European Pharmacopoeia (EP) Reference Standard
Diltiazem GNR
Diltiazem HCl
Diltiazem HCl (Tiazac)
Diltiazem Henning
Diltiazem hydrochloride (JP17/USP)
Diltiazem hydrochloride [USAN:JAN]
Diltiazem hydrochloride [USAN:USP:JAN]
Diltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)
Diltiazem hydrochloride solution, 1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material
Diltiazem hydrochloride, European Pharmacopoeia (EP) Reference Standard
Diltiazem hydrochloride, United States Pharmacopeia (USP) Reference Standard
Diltiazem Merck
Diltiazem MSD
Diltiazem Stada
Diltiazem UPSA
Diltiazem Verla
Diltiazem-Cophar
Diltiazem-GRY
Diltiazem-Isis
Diltiazem-Mepha
Diltiazem, Hydrochloride
Diltikor
Diltime
Dilzem
Dilzem Retard
Dilzem RR
Dilzene
Dilzereal 90 Retard
Dilzicardin
Dinisor
Dinisor Retard
Doclis
Dodexen
Dodexen A.P
Dodexen A.P.
Dolizem
DOV diltiazem
DTXSID8040147
Dyalac
EINECS 251-443-3
EINECS 253-918-0
Entrydil
Etizen
Etyzen
EU-0100327
Farmabes
FT-0625017
FT-0667217
Gadoserin
Hart
HDRXZJPWHTXQRI-BHDTVMLSSA-N
HE005229
Helsibon
Herben
Herbesser
Herbesser 180 SR
Herbesser 60
Herbesser 90 SR
Hesor
HMS1568K10
HY-14656
Incoril
Iski
Iski-90 SR
J-019130
J10138
Jsp006114
Kaltiazen
Kardil
KS-5089
Lacerol
Levozem
Longazem
LP00327
LS-40513
Lytelsen
Masdil
Metazem
MFCD00069252
Milptin
Miocardie
MK-793
MLS000028432
MLS001148257
MLS002222179
MolPort-003-931-523
Mono-Tildiem
Myonil
Myonil Retard
NC00558
NCGC00093768-01
NCGC00261012-01
NE54505
Novo-Diltazem
OLH94387TE
Opera_ID_79
Oxycardil
Pazeadin
Pentilzeno
Poltiazem
Presoken
Presokin A. P
Presokin A. P.
Prestwick_176
RG 83606
RG 83606 HCl
RG-83606
RT-014406
s1865
SAM002564204
SC-18679
SCHEMBL15457
Slozem
Slozen
SLV-324
SMR000058375
SR-01000075327
SR-01000075327-1
ST24046586
ST50320016
Surazem
Syn-Diltiazem
Tazem
Taztia XT
Tiadil
Tiaves
Tiazac
Tiazac extended release
Tilazem
Tilazem 90
Tilazem AS 60
Tilazem AS 90
Tildiem
Tildiem CR
Tildiem LA
Tildiem Retard
Tox21_500327
Trumsal
Ubicor
Uni Masdil
Uni-Masdil
UNII-OLH94387TE
VEN-307
Viazem SR
Viazem XL
WL Diltiazem
Zildem
Zilden
Ziruvate

US Patents and Regulatory Information for DILTIAZEM HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Teva DILTIAZEM HYDROCHLORIDE diltiazem hydrochloride CAPSULE, EXTENDED RELEASE;ORAL 074079-001 Nov 30, 1993 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Valeant Intl CARDIZEM LA diltiazem hydrochloride TABLET, EXTENDED RELEASE;ORAL 021392-002 Feb 6, 2003 AB RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Actavis Labs Fl Inc DILTIAZEM HYDROCHLORIDE diltiazem hydrochloride TABLET, EXTENDED RELEASE;ORAL 077686-006 Mar 15, 2010 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Actavis Labs Fl Inc TAZTIA XT diltiazem hydrochloride CAPSULE, EXTENDED RELEASE;ORAL 075401-002 Apr 10, 2003 AB4 RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

Expired US Patents for DILTIAZEM HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Valeant Intl CARDIZEM LA diltiazem hydrochloride TABLET, EXTENDED RELEASE;ORAL 021392-005 Feb 6, 2003 ➤ Try a Free Trial ➤ Try a Free Trial
Valeant Pharms North TIAZAC diltiazem hydrochloride CAPSULE, EXTENDED RELEASE;ORAL 020401-001 Sep 11, 1995 ➤ Try a Free Trial ➤ Try a Free Trial
Biovail DILTIAZEM HYDROCHLORIDE diltiazem hydrochloride CAPSULE, EXTENDED RELEASE;ORAL 020939-001 Jan 28, 2000 ➤ Try a Free Trial ➤ Try a Free Trial
Valeant Intl CARDIZEM CD diltiazem hydrochloride CAPSULE, EXTENDED RELEASE;ORAL 020062-004 Dec 27, 1991 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Covington
Fish and Richardson
Cipla
Healthtrust
Cantor Fitzgerald
Cerilliant
US Army
Johnson and Johnson
Teva

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.