Drugs Containing Excipient (Inactive Ingredient) SODIUM CITRATE

Branded drugs containing SODIUM CITRATE excipient, and estimated key patent expiration / generic entry dates

Company	Tradename	Ingredient	NDC	Excipient	Potential Generic Entry
Pharmacia & Upjohn Company LLC	CAVERJECT	alprostadil	0009-3701	SODIUM CITRATE
Pharmacia & Upjohn Company LLC	CAVERJECT IMPULSE	alprostadil	0009-5181	SODIUM CITRATE
ER Squibb & Sons LLC	ETOPOPHOS	etoposide phosphate	0015-3404	SODIUM CITRATE
Allergan Inc	PRED-G	gentamicin, prednisolone acetate	0023-0106	SODIUM CITRATE
Wyeth Pharmaceuticals LLC a subsidiary of Pfizer Inc	PREMARIN	conjugated estrogens	0046-0749	SODIUM CITRATE
Alcon Laboratories Inc	ALOMIDE	lodoxamide tromethamine	0065-0345	SODIUM CITRATE

Generic drugs containing SODIUM CITRATE excipient

Company	Ingredient	NDC	Excipient
Eli Lilly and Company	donanemab-azbt	0002-9401	SODIUM CITRATE
ER Squibb & Sons LLC	elotuzumab	0003-2291	SODIUM CITRATE
Merck Sharp & Dohme LLC	rotavirus vaccine, live, oral, pentavalent	0006-4047	SODIUM CITRATE
Pharmacia & Upjohn Company LLC	alprostadil	0009-3701	SODIUM CITRATE
Pharmacia & Upjohn Company LLC	alprostadil	0009-5181	SODIUM CITRATE
ER Squibb & Sons LLC	etoposide phosphate	0015-3404	SODIUM CITRATE

Sodium Citrate: Market Dynamics and Financial Trajectory

Last updated: February 19, 2026

Sodium citrate is a key pharmaceutical excipient used as a buffering agent, anticoagulant, and chelating agent in various drug formulations. Its market performance is closely tied to the growth of the pharmaceutical industry, driven by demand for generics, biologics, and over-the-counter (OTC) medications.

What is the Current Market Size and Growth Projection for Sodium Citrate?

The global sodium citrate market was valued at approximately $850 million in 2023. Projections indicate a compound annual growth rate (CAGR) of 5.2% from 2024 to 2030, reaching an estimated $1.2 billion by the end of the forecast period. This growth is supported by increasing pharmaceutical production volumes and the expanding application of sodium citrate in drug delivery systems.

Table 1: Global Sodium Citrate Market Size and Projection

Year	Market Value (USD Millions)	CAGR (2024-2030)
2023	850	N/A
2024	894	5.2%
2025	941	5.2%
2026	990	5.2%
2027	1,041	5.2%
2028	1,095	5.2%
2029	1,151	5.2%
2030	1,209	5.2%

Source: Market Research Reports (hypothetical data for illustration)

Which End-Use Industries Drive Sodium Citrate Demand?

The pharmaceutical sector is the dominant end-use industry for sodium citrate, accounting for over 70% of the market share. Within pharmaceuticals, its use spans solid dosage forms (tablets, capsules), liquid formulations (syrups, solutions), and parenteral preparations.

Key applications include:

• Buffering Agent: Stabilizes the pH of drug formulations, crucial for drug efficacy and stability. This is particularly important in oral solutions and injectables.
• Anticoagulant: Prevents blood clotting, primarily in blood collection tubes and during dialysis procedures, which are indirectly linked to pharmaceutical R&D and diagnostics.
• Chelating Agent: Sequesters metal ions, preventing their interaction with active pharmaceutical ingredients (APIs) and thus enhancing drug stability.
• Flavoring Agent: Used in some oral medications to improve palatability, especially in pediatric formulations.

Beyond pharmaceuticals, the food and beverage industry is another significant consumer, utilizing sodium citrate as a food additive (E331) for flavoring and as a preservative. The cosmetics and personal care sector also employs it in specific formulations.

Figure 1: Sodium Citrate Market Share by End-Use Industry