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Last Updated: December 15, 2019

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Drugs in Development Information for RPL554

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What is the drug development status for RPL554?

RPL554 is an investigational drug.

There have been 10 clinical trials for RPL554. The most recent clinical trial was a Phase 2 trial, which was initiated on October 1st 2015.

The most common disease conditions in clinical trials are Pulmonary Disease, Chronic Obstructive, Lung Diseases, and Lung Diseases, Obstructive. The leading clinical trial sponsors are Verona Pharma plc, Iqvia Pty Ltd, and LGC Limited.

There are ten US patents protecting this investigational drug and one hundred and fifty-three international patents.

Recent Clinical Trials for RPL554
TitleSponsorPhase
Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPDIQVIAPhase 2
Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPDLGC LimitedPhase 2
Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPDVerona Pharma plcPhase 2

See all RPL554 clinical trials

Clinical Trial Summary for RPL554

Top disease conditions for RPL554
Top clinical trial sponsors for RPL554

See all RPL554 clinical trials

US Patents for RPL554

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
RPL554   Start Trial Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors ASTRAZENECA AB (Sodertalje, SE)   Start Trial
RPL554   Start Trial Derivatives of pyrimido[6.1-a]isoquinolin-4-one Vernalis Limited (Berkshire, GB)   Start Trial
RPL554   Start Trial Derivatives of pyrimido[6,1-a]isoquinolin-4-one Rhinopharma Limited (British Columbia, CA)   Start Trial
RPL554   Start Trial Derivatives of pyrimido[6, 1-A]isoquinolin-4-one Verona Pharma PLC (London, GB)   Start Trial
RPL554   Start Trial Derivatives of pyrimido[6,1-A]isoquinolin-4-one Verona Pharma plc (London, GB)   Start Trial
RPL554   Start Trial Crystalline form of pyrimido[6,1-A] isoquinolin-4-one compound Verona Pharma plc (London, GB)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for RPL554

Drugname Country Document Number Estimated Expiration Related US Patent
RPL554 Argentina 099177 2034-01-24   Start Trial
RPL554 Australia 2015208932 2034-01-24   Start Trial
RPL554 Australia 2017200338 2034-01-24   Start Trial
RPL554 Australia 2018202956 2034-01-24   Start Trial
RPL554 Australia 2019202675 2034-01-24   Start Trial
RPL554 Canada 2935625 2034-01-24   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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