Investigational Drug Information for L-Citrulline
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What is the development status for investigational drug L-Citrulline?
L-Citrulline is an investigational drug.
There have been 34 clinical trials for L-Citrulline.
The most recent clinical trial was a Phase 3 trial, which was initiated on October 20th 2021.
The most common disease conditions in clinical trials are Anemia, Sickle Cell, Hypertension, and Acute Lung Injury. The leading clinical trial sponsors are Asklepion Pharmaceuticals, LLC, National Institutes of Health (NIH), and Vanderbilt University.
There are three hundred and ninety-one US patents protecting this investigational drug and fifteen international patents.
Summary for L-Citrulline
| US Patents | 391 |
| International Patents | 15,138 |
| US Patent Applications | 5,019 |
| WIPO Patent Applications | 0 |
| Japanese Patent Applications | 37 |
| Clinical Trial Progress | Phase 3 (2021-10-20) |
| Vendors | 109 |
Recent Clinical Trials for L-Citrulline
| Title | Sponsor | Phase |
|---|---|---|
| Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation | National Jewish Health | Phase 2 |
| Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation | United States Department of Defense | Phase 2 |
| Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation | University of Colorado, Denver | Phase 2 |
Clinical Trial Summary for L-Citrulline
Top disease conditions for L-Citrulline
Top clinical trial sponsors for L-Citrulline
US Patents for L-Citrulline
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| L-Citrulline | ⤷ Try a Trial | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | Seattle Genetics, Inc. (Bothell, WA) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Methods of expressing products in mammalian cells | INTREXON CEU, INC. (Blacksburg, VA) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Method of diagnosing and treating cancer using B-catenin splice variants | The United States of America, as represented by the Secretary, Department of Health & Human Services (Washington, DC) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Seaweed-derived cosmetic compositions | Skinergistics Clinical Skin Solutions Inc. (Vancouver, CA) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Therapeutic compounds and methods of use thereof | GENENTECH, INC. (South San Francisco, CA) XENON PHARMACEUTICALS INC. (Burnaby, BC, CA) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Methods for control of flux in metabolic pathways through enzyme relocation | The Board of Trustees of the Leland Stanford Junior University (Stanford, CA) GreenLight Biosciences, Inc. (Medford, MA) | ⤷ Try a Trial |
| L-Citrulline | ⤷ Try a Trial | Hair dyeing process using at least one ortho-diphenol and one organic salt of titanium and of a carboxylic acid | L'OREAL (Paris, FR) | ⤷ Try a Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for L-Citrulline
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| L-Citrulline | Australia | AU2007345497 | 2027-01-29 | ⤷ Try a Trial |
| L-Citrulline | Canada | CA2676865 | 2027-01-29 | ⤷ Try a Trial |
| L-Citrulline | European Patent Office | EP2114986 | 2027-01-29 | ⤷ Try a Trial |
| L-Citrulline | Spain | ES2425575 | 2027-01-29 | ⤷ Try a Trial |
| L-Citrulline | World Intellectual Property Organization (WIPO) | WO2008092281 | 2027-01-29 | ⤷ Try a Trial |
| L-Citrulline | Australia | AU2006269422 | 2025-07-07 | ⤷ Try a Trial |
| L-Citrulline | Canada | CA2614436 | 2025-07-07 | ⤷ Try a Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
