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Drugs in Development Information for Entinostat
What is the drug development status for Entinostat?
Entinostat is an investigational drug.
There have been 62 clinical trials for Entinostat.
The most recent clinical trial was a Phase 2 trial, which was initiated on May 15th 2018.
The most common disease conditions in clinical trials are Breast Neoplasms, Carcinoma, and Lung Neoplasms. The leading clinical trial sponsors are Syndax Pharmaceuticals, National Cancer Institute (NCI), and Merck Sharp & Dohme Corp.
There are one hundred and forty-seven US patents protecting this investigational drug and one international patent.
Summary for Entinostat
| US Patents | 147 |
| International Patents | 1,406 |
| US Patent Applications | 489 |
| WIPO Patent Applications | 307 |
| Japanese Patent Applications | 3 |
| Clinical Trial Progress | Phase 2 (2018-05-15) |
| Vendors | 86 |
Recent Clinical Trials for Entinostat
| Title | Sponsor | Phase |
|---|---|---|
| Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
| Molibresib and Entinostat in Treating Patients With Advanced or Refractory Solid Tumors or Lymphomas | National Cancer Institute (NCI) | Phase 1 |
| Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers | AstraZeneca | Phase 1/Phase 2 |
Clinical Trial Summary for Entinostat
Top disease conditions for Entinostat
Top clinical trial sponsors for Entinostat
US Patents for Entinostat
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| Entinostat | Start Trial | Heat shock protein 70 (hsp-70) receptor ligands | Duke University (Durham, NC) | Start Trial |
| Entinostat | Start Trial | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III | Frequency Therapeutics, Inc. (Woburn, MA) | Start Trial |
| Entinostat | Start Trial | Liposomal compositions of epoxyketone-based proteasome inhibitors | Onyx Therapeutics, Inc. (Thousand Oaks, CA) | Start Trial |
| Entinostat | Start Trial | Oxabicycloheptanes and oxabicycloheptenes, their preparation and use | Lixte Biotechnology, Inc. (East Setauket, NY) | Start Trial |
| Entinostat | Start Trial | Substituted 6-aminopurines for targeting HSP90 | Duke University (Durham, NC) | Start Trial |
| Entinostat | Start Trial | Cyclodextrin complexation methods for formulating peptide proteasome inhibitors | Onyx Therapeutics, Inc. (Thousand Oaks, CA) | Start Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for Entinostat
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| Entinostat | World Intellectual Property Organization (WIPO) | 2015148714 | 2034-03-25 | Start Trial |
| Entinostat | Australia | 2013292636 | 2032-07-18 | Start Trial |
| Entinostat | Australia | 2013292647 | 2032-07-18 | Start Trial |
| Entinostat | Australia | 2018201445 | 2032-07-18 | Start Trial |
| Entinostat | Canada | 2879139 | 2032-07-18 | Start Trial |
| Entinostat | Canada | 2879208 | 2032-07-18 | Start Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
