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Drugs in Development Information for Entinostat
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What is the drug development status for Entinostat?
Entinostat is an investigational drug.
There have been 64 clinical trials for Entinostat.
The most recent clinical trial was a Phase 2 trial, which was initiated on March 1st 2014.
The most common disease conditions in clinical trials are Breast Neoplasms, Carcinoma, and Lung Neoplasms. The leading clinical trial sponsors are Syndax Pharmaceuticals, National Cancer Institute (NCI), and Merck Sharp & Dohme Corp.
There are one hundred and fifty-four US patents protecting this investigational drug and one international patent.
Summary for Entinostat
| US Patents | 154 |
| International Patents | 1,465 |
| US Patent Applications | 501 |
| WIPO Patent Applications | 1,766 |
| Japanese Patent Applications | 3 |
| Clinical Trial Progress | Phase 2 (2014-03-01) |
| Vendors | 89 |
Recent Clinical Trials for Entinostat
| Title | Sponsor | Phase |
|---|---|---|
| Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread | National Cancer Institute (NCI) | Phase 1 |
| BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT) | National Cancer Institute (NCI) | Phase 1 |
| Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
Clinical Trial Summary for Entinostat
Top disease conditions for Entinostat
Top clinical trial sponsors for Entinostat
US Patents for Entinostat
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| Entinostat | Start Trial | Heat shock protein 70 (hsp-70) receptor ligands | Duke University (Durham, NC) | Start Trial |
| Entinostat | Start Trial | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III | Frequency Therapeutics, Inc. (Woburn, MA) | Start Trial |
| Entinostat | Start Trial | Liposomal compositions of epoxyketone-based proteasome inhibitors | Onyx Therapeutics, Inc. (Thousand Oaks, CA) | Start Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for Entinostat
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| Entinostat | World Intellectual Property Organization (WIPO) | WO2015148714 | 2034-03-25 | Start Trial |
| Entinostat | Australia | AU2013292636 | 2032-07-18 | Start Trial |
| Entinostat | Australia | AU2013292647 | 2032-07-18 | Start Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
