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Last Updated: January 19, 2022

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Investigational Drug Information for Entinostat


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What is the drug development status for Entinostat?

Entinostat is an investigational drug.

There have been 69 clinical trials for Entinostat. The most recent clinical trial was a Phase 2 trial, which was initiated on March 29th 2014.

The most common disease conditions in clinical trials are Breast Neoplasms, Carcinoma, and Lung Neoplasms. The leading clinical trial sponsors are National Cancer Institute (NCI), Syndax Pharmaceuticals, and Merck Sharp & Dohme Corp.

There are six hundred and eighty-four US patents protecting this investigational drug and six international patents.

Recent Clinical Trials for Entinostat
TitleSponsorPhase
Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors and LymphomasNational Cancer Institute (NCI)Phase 1/Phase 2
Phase I/II Trial of the Combination of Bintrafusp Alfa (M7824), Entinostat and NHS-IL12 (M9241) in Patients With Advanced CancerNational Cancer Institute (NCI)Phase 1/Phase 2
BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)National Cancer Institute (NCI)Phase 1

See all Entinostat clinical trials

Clinical Trial Summary for Entinostat

Top disease conditions for Entinostat
Top clinical trial sponsors for Entinostat

See all Entinostat clinical trials

US Patents for Entinostat

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Entinostat ⤷  Try it Free Heat shock protein 70 (hsp-70) receptor ligands Duke University (Durham, NC) ⤷  Try it Free
Entinostat ⤷  Try it Free Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines Signal Pharmaceuticals, LLC (San Diego, CA) ⤷  Try it Free
Entinostat ⤷  Try it Free Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells Selecta Biosciences, Inc. (Watertown, MA) ⤷  Try it Free
Entinostat ⤷  Try it Free Pyrrolidinone derivatives as MetAP-2 inhibitors Merck Patent GmbH (Darmstadt, DE) ⤷  Try it Free
Entinostat ⤷  Try it Free Pharmaceutical formulations of a bruton's tyrosine kinase inhibitor Pharmacyclics LLC (Sunnyvale, CA) ⤷  Try it Free
Entinostat ⤷  Try it Free Anti-CS1 antibodies and antibody drug conjugates AbbVie Biotherapeutics Inc. (Redwood City, CA) ⤷  Try it Free
Entinostat ⤷  Try it Free Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III Frequency Therapeutics, Inc. (Woburn, MA) ⤷  Try it Free
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Entinostat

Drugname Country Document Number Estimated Expiration Related US Patent
Entinostat World Intellectual Property Organization (WIPO) WO2015148714 2034-03-25 ⤷  Try it Free
Entinostat European Patent Office EP3131552 2034-04-16 ⤷  Try it Free
Entinostat Spain ES2823756 2034-04-16 ⤷  Try it Free
Entinostat Japan JP2017514806 2034-04-16 ⤷  Try it Free
Entinostat Japan JP2019070012 2034-04-16 ⤷  Try it Free
Entinostat Japan JP2021059548 2034-04-16 ⤷  Try it Free
Entinostat Japan JP6838085 2034-04-16 ⤷  Try it Free
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Boehringer Ingelheim
Dow
McKesson
Merck
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.