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Harvard Business School
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Last Updated: October 19, 2019

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Drugs in Development Information for Alisertib

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Drug Development Status for Alisertib: Patents, clinical trial progress, indications

Alisertib is an investigational drug.

There have been 47 clinical trials for Alisertib. The most recent clinical trial was a Phase 2 trial, which was initiated on June 1st 2012.

The most common disease conditions in clinical trials are Lymphoma, Neoplasms, and Adenocarcinoma. The leading clinical trial sponsors are Millennium Pharmaceuticals, Inc., National Cancer Institute (NCI), and Takeda.

There are fifteen US patents protecting this investigational drug and one hundred and ninety-four international patents.

Recent Clinical Trials for Alisertib
TitleSponsorPhase
Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung CancerTakedaPhase 1
Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung CancerCollin BlakelyPhase 1
Romidepsin Versus Combination of Romidepsin Plus Pralatrexate in PTCLColumbia UniversityPhase 3

See all Alisertib clinical trials

Clinical Trial Summary for Alisertib

Top disease conditions for Alisertib
Top clinical trial sponsors for Alisertib

See all Alisertib clinical trials

US Patents for Alisertib

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Alisertib   Start Trial Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido [5,4-D][2]benzazepin-2-YL]amino}-2-methoxybenzoate Millennium Pharmaceuticals, Inc. (Cambridge, MA)   Start Trial
Alisertib   Start Trial Combinations of LSD1 inhibitors for use in the treatment of solid tumors Oryzon Genomics, S.A. (Madrid, ES)   Start Trial
Alisertib   Start Trial Aurora kinase inhibitors for inhibiting mitotic progression Millennium Pharmaceuticials, Inc. (Cambridge, MA)   Start Trial
Alisertib   Start Trial Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-D][2]benzazepin- -2-yl]amino}-2-methoxybenzoate Millennium Pharmaceuticals, Inc. (Cambridge, MA)   Start Trial
Alisertib   Start Trial Pharmaceutical compositions for the treatment of cancer and other diseases or disorders Millennium Pharmaceuticals, Inc. (Cambridge, MA)   Start Trial
Alisertib   Start Trial Solid pharmaceutical compositions and processes for their production MILLENNIUM PHARMACEUTICALS, INC. (Cambridge, MA)   Start Trial
Alisertib   Start Trial Tetrazolones as a carboxylic acid bioisosteres Rigel Pharmaceuticals, Inc. (South San Francisco, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Alisertib

Drugname Country Document Number Estimated Expiration Related US Patent
Alisertib Brazil 112012020557 2030-02-19   Start Trial
Alisertib Canada 2788774 2030-02-19   Start Trial
Alisertib China 102770024 2030-02-19   Start Trial
Alisertib China 104031049 2030-02-19   Start Trial
Alisertib European Patent Office 2536279 2030-02-19   Start Trial
Alisertib Japan 2013520424 2030-02-19   Start Trial
Alisertib Japan 2015180679 2030-02-19   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

McKinsey
Moodys
Mallinckrodt
Johnson and Johnson
Merck
Boehringer Ingelheim

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