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Last Updated: August 14, 2020

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CLINICAL TRIALS PROFILE FOR TRV130

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Clinical Trials for TRV130

Trial ID Title Status Sponsor Phase Summary
NCT01514578 Single Ascending Dose Study of Intravenous TRV130A in Healthy Adult Males Completed Trevena Inc. Phase 1 This study will evaluate the safety, blood levels, and effects of TRV130A on pain perception and sedation in healthy adult males.
NCT02083315 Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects Completed Trevena Inc. Phase 1 This study is designed to compare TRV130 to placebo and morphine to learn about its effects on pain relief and side effects.
NCT02100748 A Study of TRV130 for the Treatment of Pain After Bunionectomy Completed Trevena Inc. Phase 2 The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain after bunionectomy.
NCT02169934 A Study to Investigate the Metabolism and Excretion of [14C]-TRV130 in Healthy Male Subjects Completed Trevena Inc. Phase 1 The purpose of this study is to determine the routes of excretion for TRV130 and it's metabolites, and to determine and characterize, structurally, the metabolites present in plasma, urine, and feces in healthy male subjects.
NCT02335294 A Study of TRV130 for the Treatment of Pain After Abdominoplasty Completed Lotus Clinical Research, LLC Phase 2 The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain following abdominoplasty.
NCT02335294 A Study of TRV130 for the Treatment of Pain After Abdominoplasty Completed Trevena Inc. Phase 2 The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain following abdominoplasty.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for TRV130

Condition Name

Condition Name for
Intervention Trials
Acute Pain 4
Healthy 3
Pain 2
Pain, Acute 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Acute Pain 5
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Clinical Trial Locations for TRV130

Trials by Country

Trials by Country for
Location Trials
United States 21
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Trials by US State

Trials by US State for
Location Trials
Texas 5
Maryland 4
Utah 3
California 3
Arizona 3
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Clinical Trial Progress for TRV130

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 3
Phase 2 3
Phase 1 4
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 6
Recruiting 4
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Clinical Trial Sponsors for TRV130

Sponsor Name

Sponsor Name for
Sponsor Trials
Trevena Inc. 10
Kestrel Biologic 1
Lotus Clinical Research, LLC 1
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 10
Other 2
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