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Last Updated: October 2, 2022

CLINICAL TRIALS PROFILE FOR PYRROLE-2-CARBOXYLATE


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Clinical Trials for Pyrrole-2-Carboxylate

Trial ID Title Status Sponsor Phase Summary
NCT03089606 ↗ Pembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging Biomarker Active, not recruiting Merck Sharp & Dohme Corp. Phase 2 Explore association between intensity of C11-AMT PET at baseline, as measured by mean standardized uptake value (SUVmax at each lesion), total tumor metabolic volume, measurement of intra-tumoral and inter-lesional heterogeneity), with objective response rate (ORR) at 12 weeks (as defined via RECIST 1.1) to pembrolizumab in patients with treatment-naïve metastatic melanoma.
NCT03089606 ↗ Pembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging Biomarker Active, not recruiting UNC Lineberger Comprehensive Cancer Center Phase 2 Explore association between intensity of C11-AMT PET at baseline, as measured by mean standardized uptake value (SUVmax at each lesion), total tumor metabolic volume, measurement of intra-tumoral and inter-lesional heterogeneity), with objective response rate (ORR) at 12 weeks (as defined via RECIST 1.1) to pembrolizumab in patients with treatment-naïve metastatic melanoma.
NCT04112160 ↗ Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal Completed University of Texas Southwestern Medical Center Phase 2 This is a prospective randomized double-blind controlled trial assessing the benefits of intramuscular ketorolac before or immediately after office ureteral stent removal.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Pyrrole-2-Carboxylate

Condition Name

Condition Name for
Intervention Trials
Breast Cancer 2
Melanoma 1
Pain 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Breast Neoplasms 2
Venous Thrombosis 1
Thrombosis 1
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Clinical Trial Locations for Pyrrole-2-Carboxylate

Trials by Country

Trials by Country for
Location Trials
China 3
United States 2
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Trials by US State

Trials by US State for
Location Trials
Texas 1
North Carolina 1
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Clinical Trial Progress for Pyrrole-2-Carboxylate

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 4 1
Phase 2 4
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Recruiting 2
Active, not recruiting 1
Unknown status 1
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Clinical Trial Sponsors for Pyrrole-2-Carboxylate

Sponsor Name

Sponsor Name for
Sponsor Trials
West China Hospital 2
UNC Lineberger Comprehensive Cancer Center 1
University of Texas Southwestern Medical Center 1
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Sponsor Type

Sponsor Type for
Sponsor Trials
Other 6
Industry 2
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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Baxter
Harvard Business School
Mallinckrodt
Express Scripts
McKesson

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