The purpose of this study is to measure how much of the study drug (evacetrapib) gets into
the blood stream and how long it takes the body to get rid of it when given with
gemfibrozil. Each participant will receive gemfibrozil alone, evacetrapib alone, and both
drugs in combination. There is no washout period between doses. The safety of both of the
study drugs given together will be evaluated. Information about any side effects that may
occur will also be collected. This study will last approximately 36 days.
A Study of Evacetrapib in Healthy Female Participants
Eli Lilly and Company
The purpose of this study is to evaluate the effects of evacetrapib on oral contraceptives
(Ortho-Cyclen®) when given to healthy female participants. The amount of female hormones
found in the blood will be measured and compared when taken alone and when taken with
evaceptrapib. Each woman will participate in two study periods. Information about any side
effects that may occur will also be collected.
Study of Food on Evacetrapib (LY2484595) in Healthy Participants
Eli Lilly and Company
The purpose of this study is to measure how much of the drug gets into the blood stream and
how long it takes the body to get rid of it when given to healthy participants. Information
about any side effects that may occur will also be collected.
The study has 2 periods. In each period, participants will take the study drug for 10 days,
either with or without a meal. There is a minimum 14 day washout between each period.
This study is approximately 50 days, not including screening. Screening is required within
28 days prior to the start of the study.
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