DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR BCT197

« Back to Dashboard

Clinical Trials for BCT197

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01332097	Safety & Efficacy of BCT197A2201 in Chronic Obstructive Pulmonary Disease (COPD) Patients Presenting With an Exacerbation	Completed	Novartis Pharmaceuticals	Phase 2	This study will assess preliminary parameters of safety and efficacy of a single dose of BCT197 in patients with a Chronic Obstructive Pulmonary Disease (COPD) exacerbation.
NCT01336959	Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery	Terminated	Novartis Pharmaceuticals	Phase 2	This study will assess the safety and efficacy of BCT197 on acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass.
NCT02700919	Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease	Recruiting	Mereo BioPharma	Phase 2	The purpose of this study is to compare the efficacy and safety of BCT197 when added on to standard of care in adult subjects with acute respiratory exacerbations of chronic obstructive pulmonary disease requiring hospitalization. Additionally, the study will characterize the pharmacokinetics of BCT197 in adults with COPD. The total duration of the study will be 26 weeks. Subjects will receive study treatment administration over a period of 5 days after randomization. It is expected that approximately 255 subjects will complete the study and follow-up.
NCT02926326	The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers	Completed	Mereo BioPharma	Phase 1	An open-label, single-sequence study to evaluate the effect of azithromycin on BCT197 exposure in healthy male subjects.
NCT03498170	The Effect of Itraconazole on BCT197 Exposure in Healthy Male Participants	Completed	Mereo BioPharma	Phase 1	An Open-label, 2-period, Single-sequence, Crossover Study to Evaluate the Effect of Multiple Oral Dosing of Itraconazole on BCT197 Systemic Exposure in Healthy Male Participants.

Clinical Trial Conditions for BCT197

Condition Name

Condition Name for
Intervention	Trials
Interaction	2
Pulmonary Disease, Chronic Obstructive	1
Chronic Obstructive Pulmonary Disease	1
Acute Kidney Injury	1

Condition MeSH

Condition MeSH for
Intervention	Trials
Lung Diseases, Obstructive	2
Lung Diseases	2
Pulmonary Disease, Chronic Obstructive	2
Chronic Disease	1

Clinical Trial Locations for BCT197

Trials by Country

Trials by Country for
Location	Trials
United States	20
United Kingdom	2
Bulgaria	2
Russian Federation	2
Romania	2

Trials by US State

Trials by US State for
Location	Trials
Florida	2
California	2
Pennsylvania	2
Texas	1
Iowa	1

Clinical Trial Progress for BCT197

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 2	3
Phase 1	2

Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	3
Recruiting	1
Terminated	1

Clinical Trial Sponsors for BCT197

Sponsor Name

Sponsor Name for
Sponsor	Trials
Mereo BioPharma	3
Novartis Pharmaceuticals	2

Sponsor Type

Sponsor Type for
Sponsor	Trials
Industry	5