A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms
The purpose of the study is to evaluate safety and tolerability of arbaclofen placarbil
sustained release tablets taken every 12 hours compared to placebo in subjects with acute
back spasms in the lumbar region.
A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)
The purpose of the study is to evaluate efficacy and safety of arbaclofen placarbil
(XP19986) versus placebo as adjunctive therapy in subjects with troublesome GERD symptoms
despite therapy with approved doses of a Proton Pump Inhibitor (PPI).
A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
This study will determine the maximum tolerated dose (MTD) of arbaclofen placarbil (AP) in
the treatment of subjects with Alcohol Use Disorder (AUD). For every two subjects receiving
AP, one subject will receive placebo.
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