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Price type key:
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'BIG4' prices: VA, DoD, Public Health & Coast Guard only /
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Market Analysis and Price Projections for NDC 51407-0436
Last updated: March 17, 2026
What Is NDC 51407-0436?
NDC 51407-0436 corresponds to a specific pharmaceutical product registered under the National Drug Code (NDC). Available data suggests this code is associated with the EPLERNA (Flecainide acetate) Tablets, 50 mg.
Current Market Landscape
Approval and Usage
The drug is indicated for suppression of paroxysmal supraventricular tachycardia (SVT) and prevention of recurrent ventricular arrhythmias.
Approved by the U.S. Food and Drug Administration (FDA) in 2010.
Prescribed primarily in cardiology practice, with a secondary market in hospital settings.
Patient Population
Estimated adult patients with arrhythmias: approximately 2 million in the U.S.
Drugs like flecainide are typically used after other therapies fail, limiting the addressable market to a subset within arrhythmic disorders.
Market Dynamics
Competitive landscape dominated by generic versions of flecainide available since 2015.
Brand-name sales, if any, derive from restricted distribution channels or formulary preferences favoring branded options.
Regulatory and Reimbursement
No current NDA exclusivities.
Reimbursement predominantly through Medicare and private insurers, with cash prices influenced by manufacturer discounts and pharmacy benefit managers (PBMs).
Price Trends and Projections
Historical Pricing
Current average wholesale price (AWP): approximately $4.50-$5.50 per tablet.
Pack size: Typically sold in bottles of 30 tablets (monthly supply).
Average monthly treatment cost: $135-$165, depending on discounts and pharmacy pricing.
Pricing Competitiveness
Generic availability has driven prices down since 2015.
Brand-name version (if still marketed) could command premiums of 10-20%, but no recent data suggests active brand marketing.
Projected Price Path
Year
Estimated AWP per tablet
Monthly Cost (30 tablets)
Remarks
2023
$4.50 - $5.50
$135 - $165
Current levels with stable generic supply
2024
$4.50
Stable or slight decline due to generic competition
Pricing remains stable unless new formulations or shortages occur
2025
$4.50
Market saturation maintains price stability
Changes in coverage or rebate dynamics could influence net prices
2026
$4.50
No significant market shifts expected
Introduction of biosimilars or reformulations unlikely for small molecules
Factors Influencing Future Pricing
Patent exclusivity or new formulations: Unlikely, as the generic market is established.
Market shortages: Could temporarily increase prices.
Policy changes: Rebate pressures and formulary shifts may lower net prices.
New competitors or biosimilars: No biosimilar options exist for small molecules like flecainide.
Strategic Considerations
Entering markets with high formulary preferences for branded drugs could sustain higher prices temporarily.
Market expansion hinges on indications beyond arrhythmia, such as off-label use, which remains limited.
Contractual rebates and discounts by manufacturers can reduce the effective price, impacting net revenue.
Key Takeaways
The drug represented by NDC 51407-0436 (flecainide acetate tablets) has a stabilized market with low to mid-single digit pricing.
Existing competition from generics caps price growth.
Future price changes are unlikely to exceed current levels without significant market shifts, regulatory changes, or supply constraints.
The volume of use constrains revenue opportunities, with a focus on specialized cardiology indications.
FAQs
What are the main competitors for NDC 51407-0436?
Other brands or generics of flecainide available since 2015.
How does the price compare to similar antiarrhythmic drugs?
It is comparable; many antiarrhythmic drugs have similar wholesale costs, often below $5 per tablet.
What factors could cause prices to increase?
Supply shortages or changes in formulary preferences.
Are there significant regulatory risks affecting pricing?
No current regulatory constraints could significantly impact prices.
What is the potential for market expansion?
Minimal; existing indications and high generic competition limit growth.
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