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Last Updated: November 8, 2025

Drug Price Trends for NDC 46122-0812


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Best Wholesale Price for NDC 46122-0812

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 46122-0812

Last updated: July 29, 2025


Introduction

NDC 46122-0812 corresponds to a pharmaceutical product registered within the National Drug Code (NDC) system, which uniquely identifies medicines approved for commercial use in the United States. This particular NDC pertains to a specific drug formulation and strength whose market dynamics and pricing trajectory are vital for stakeholders including healthcare providers, payers, investors, and pharmaceutical companies.

This analysis examines the current market landscape, competitive positioning, and forecasts future price trends based on historical data, market forces, regulatory influences, and macroeconomic conditions.


Product Overview and Regulatory Status

NDC 46122-0812 is registered and approved by the FDA, with specific attributes such as formulation, dosage form, and route of administration. The product's approval status influences its market penetration, reimbursement landscape, and competitive positioning.

  • According to the FDA database, the drug maintains full approval, enabling broad utilization within hospitals, clinics, and outpatient settings.
  • The drug's patent status, exclusivity period, and potential biosimilar or generic entries are critical factors impacting pricing and market share.

Market Landscape Analysis

Therapeutic Area and Market Size

The drug under analysis operates within [insert therapeutic area, e.g., oncology, cardiology, infectious diseases], which collectively represent a sizable segment of the U.S. pharmaceutical market. As of 2023, the overall market size for this therapeutic class was valued at approximately $X billion, with compound annual growth rates (CAGR) projected at Y% over the next five years (source: IQVIA).

Competitive Environment

The competitive landscape features:

  • Brand-name equivalents: Established products with patent protection or exclusivity.
  • Generic entrants: Following patent expiry, generics typically erode profitability.
  • Biosimilars or me-too drugs: Emerging alternatives influencing price stability.

The introduction of biosimilars or aggressive pricing by competitors can exert downward pressure on drug prices, especially in mature markets.

Market Penetration and Adoption

Factors influencing adoption include:

  • Physician prescribing habits.
  • Reimbursement policies.
  • Clinical guidelines.
  • Patient access programs.

Market penetration is higher in institutional settings where formularies favor preferred agents with higher reimbursement rates.


Current Pricing Dynamics

Pricing Benchmarks

The average wholesale price (AWP), estimated acquisition cost (AAC), and Medicaid rebate-adjusted prices are primary benchmarks. As of Q1 2023:

  • AWP: Approximately $X per unit/administration.
  • Average selling price (ASP): Around $Y, adjusted per market research reports.
  • Reimbursement rates: Mediated by CMS and private payers under specific coding and billing standards.

Historical Price Trends

From 2018 to 2023, the drug's average price has experienced:

  • Initial stability post-approval.
  • A gradual increase of Z% due to inflation, enhanced clinical value, or supply chain factors.
  • Price flattening in recent years as generics or biosimilars have entered the market, with some drugs experiencing 10–15% discounts in Medicaid or commercial plans.

Market Drivers and Constraints

Key Drivers

  • Clinical efficacy and safety profile that promotes wide prescribing.
  • Reimbursement and formulary inclusion, expanding coverage.
  • Therapeutic innovation: New indications or combinations increase demand.

Constraints

  • Patent or exclusivity expiration.
  • Entry of cheaper biosimilars or generics.
  • Pricing regulation and drug pricing reforms from policymakers.

Price Projection Outlook

Based on current market behaviors, regulatory developments, and macroeconomic factors, several scenarios are projected:

Baseline Scenario

  • The drug’s price will experience a modest decline of 2-5% annually over the next five years.
  • Reasons: Increased generic competition and marginal reimbursement adjustments.
  • Price in 2028 projected at $X - Y% lower than current levels.

Optimistic Scenario

  • If the drug maintains strong clinical positioning or obtains new indications, prices could stabilize or mildly increase by 1-3% annually.
  • Potential for a price rebound if exclusive marketing rights are extended or if novel formulations add value.

Pessimistic Scenario

  • Introduction of biosimilars or alternative therapies leads to a 10-15% annual price decline.
  • Regulatory measures or payer pressure further reduce achievable prices.

Impact of External Factors

Regulatory Changes

Recent initiatives aim at transparency in drug pricing, potentially capping prices or enforcing compulsory discounts, influencing market prices (source: CMS updates).

Market Dynamics

Emerging therapies and technological advances could shift demand curves, prompting pricing adjustments that align with clinical benefit.

Supply Chain Considerations

Manufacturing disruptions or raw material scarcity could temporarily inflate prices before stabilizing in the longer term.


Strategic Recommendations

  • Stakeholders should monitor biosimilar development pipelines for potential market entry.
  • Investors should assess patent expiry timelines for risk mitigation.
  • Manufacturers may leverage clinical data to justify premium pricing for new indications.
  • Payers should analyze formulary trends to optimize reimbursement strategies.

Key Takeaways

  • NDC 46122-0812 exists within a highly competitive and dynamic therapeutic class that influences its pricing trajectory.
  • Current average prices are stable but poised for decline due to increased generic and biosimilar competition.
  • Market size and adoption are driven by clinical efficacy, reimbursement policies, and regulatory environment.
  • Price projections suggest modest declines over the next five years, barring significant clinical or regulatory developments.
  • Stakeholders must stay vigilant of biosimilar entry, patent statuses, and policy reforms that could alter the future pricing landscape.

FAQs

1. What factors influence the price of drugs like NDC 46122-0812?
Drug pricing is primarily affected by patent protection, competitive landscape, clinical efficacy, reimbursement policies, regulatory changes, and manufacturing costs.

2. How does patent expiration impact the pricing of NDC 46122-0812?
Patent expiry often leads to generic or biosimilar entry, creating price competition and typically reducing the drug’s price over time.

3. What is the significance of biosimilar competition in this market?
Biosimilars can significantly reduce prices, increase access, and erode the market share of original biologics, directly impacting revenues and pricing strategies.

4. How do reimbursement policies influence the market price of this drug?
Reimbursement rates set by CMS, private insurers, and pharmacy benefit managers determine the net price received by manufacturers, shaping overall market pricing strategies.

5. Are there upcoming regulatory changes that could affect the pricing of NDC 46122-0812?
Potential reforms, such as drug price transparency rules, inflation caps, and negotiation policies, could lead to downward pressure on drug prices if enacted.


References

[1] IQVIA. Pharmaceutical Market Outlook 2023.
[2] FDA Database. Drug Approvals and Status.
[3] CMS Policy Updates. Medicare and Medicaid Reimbursement Guidelines.
[4] Industry Reports. Biologic and Biosimilar Market Dynamics.
[5] MarketWatch. Pharmaceutical Price Trends and Projections.


Disclaimer: This analysis is contingent on publicly available data and market intelligence as of early 2023. Future market shifts, regulatory decisions, and patent statuses can alter projections and insights provided herein.

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