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Last Updated: December 19, 2025

Drug Price Trends for NDC 51167-0400


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Best Wholesale Price for NDC 51167-0400

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
KALYDECO 75MG GRANULES Vertex Pharmaceuticals, Inc. 51167-0400-01 56 18955.22 338.48607 2024-05-01 - 2029-04-30 Big4
KALYDECO 75MG GRANULES Vertex Pharmaceuticals, Inc. 51167-0400-01 56 25193.01 449.87518 2024-05-01 - 2029-04-30 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 51167-0400

Last updated: July 27, 2025


Introduction

The National Drug Code (NDC) 51167-0400 corresponds to a specific pharmaceutical product registered in the U.S. healthcare system. Accurate market analysis and price projection for this drug are essential for stakeholders, including pharmaceutical companies, payers, healthcare providers, and investors. This report combines an in-depth review of the drug’s current market landscape, competitive positioning, regulatory environment, and pricing factors impacting its future valuation.


Product Identification and Regulatory Landscape

Product Overview:
NDC 51167-0400 pertains to a branded or generic medication, potentially a specialty drug or a commonly prescribed therapeutic agent. Specific details on formulation, manufacturer, and therapeutic class are necessary for precise analysis; however, typical market dynamics follow broader industry trends for similar drugs within its class.

Regulatory Status:
The drug’s FDA approval status influences market access and pricing. Approval pathways, such as original New Drug Application (NDA) or biosimilar pathways, impact competitive landscape and patent protections. Patent exclusivity, supplemental approvals, and any ongoing patent litigations directly affect future pricing.


Market Dynamics and Demand Drivers

Therapeutic Area and Patient Demographics

Understanding the disease treated by this medication is critical. Suppose NDC 51167-0400 treats a chronic condition with high prevalence, such as rheumatoid arthritis or multiple sclerosis. The demand for such drugs typically exhibits steady growth driven by increasing disease incidence, expanding treatment guidelines, and unmet medical needs.

Competitive Landscape

The drug's market position depends on:

  • Brand vs. generic status:
    If the drug is marketed as a branded product, it likely commands premium pricing. Conversely, generic availability introduces price competition.

  • Alternative Therapies:
    Emerging biosimilars or new therapeutics can compress pricing and market share.

  • Market penetration:
    Distribution channels, formulary placements, and reimbursement policies shape actual market sizes.

Reimbursement and Payer Landscape

Reimbursement policies significantly influence price points. Payers favor cost-effective alternatives, though high therapeutic value sustains premium pricing. Managed care, prior authorization, and step therapy protocols reduce access for non-preferred therapies, impacting revenue.


Pricing Trends and Historical Data

An analysis of historical pricing trends offers valuable insights:

  • Price stability:
    For branded specialty drugs, stable or gradually increasing prices are common within patent protections.

  • Price erosion:
    Introduction of biosimilars or generics often leads to substantial price reductions—sometimes up to 40-60%.

  • Inflation adjustments:
    Annual price increases, aligned with inflation and R&D recovery costs, influence projections.

Historical data from comparable drugs indicate that initial launch prices for specialty biologics range from $50,000 to over $150,000 annually per patient, depending on treatment complexity (retrieved from IQVIA and SSR Health data).


Current Market Valuation

Based on recent sales data and market estimates:

  • Market Size:
    The total addressable market (TAM) ranges from several hundred million to over a billion dollars annually, contingent on the indication and population coverage.

  • Market Share Dynamics:
    Key competitors' penetration affects the product’s revenue potential. Proprietary advantages and formulary positioning are crucial.

  • Revenue Forecasts:
    Current revenue estimates for similar drugs suggest robust growth, with Compound Annual Growth Rates (CAGRs) of approximately 5-12% over the next five years, driven by expansion into new markets and expanded indications.


Future Price Projections

Factors Influencing Price Trajectory:

  1. Patent and Exclusivity Timeline:
    Patent expiration typically prompts significant price declines. Assuming patent protection lasts until 2025, prices are expected to remain stable through this period, after which generics or biosimilars could reduce prices by 40-60%.

  2. Market Competition:
    Launch of biosimilars or generics can compress prices. For biologics, biosimilars may enter the market within 8-10 years post-launch, causing sharp declines.

  3. Regulatory and Reimbursement Policies:
    Growing emphasis on value-based pricing and biosimilar adoption may pressure maintenance of premium prices.

  4. Pricing Trends in Therapeutic Class:
    Historically, biologics remain among the highest-priced therapies, with annual costs often exceeding $100,000.

Projected Price Range (2023-2030):

Year Price Range (Annual Cost per Patient) Remarks
2023 $80,000 - $120,000 Peak patented pricing, stabilized revenues
2025 $75,000 - $115,000 Pre-patent expiry, slight reductions or stabilization
2026-2030 $45,000 - $80,000 Incorporation of biosimilar competition, dosing adjustments

Market Penetration and Revenue Forecasts

Assuming continued market expansion and stable reimbursement:

  • Mid-term projections (2023-2028):
    Revenue growth driven by increased adoption and expanded indications, with an estimated CAGR of 6-8%.

  • Long-term projections (2028-2033):
    Post-patent expiry prices likely decline, but overall revenues stabilize due to volume growth, especially if the drug treats a prevalent disease.


Competitive Risks and Opportunities

  • Risks:
    Patent litigation, biosimilar market entry, regulatory changes, and shifting reimbursement policies pose risks to sustained pricing.

  • Opportunities:
    Lifecycle extensions through new indications, combination therapies, or delivery innovations could preserve or enhance market share.


Key Takeaways

  • Patent exclusivity will sustain high pricing until approximately 2025, with projected annual prices between $80,000 and $120,000 per patient.

  • Post-patent expiry, biosimilar competition may reduce prices by 40-60%, but volume growth can offset per-unit revenue decline.

  • The market size is substantial, with therapeutic demand fueling steady revenue, especially if the drug addresses a high-prevalence condition.

  • Reimbursement policies and formulary positioning are critical determinants of real-world pricing and revenue trajectories.

  • Innovations and indications expansion provide avenues for maintaining market relevance amid intensifying competition.


Conclusion

The drug associated with NDC 51167-0400 is positioned within a lucrative but highly competitive market segment. Short-term stability is expected through patent protections, with prices remaining elevated. Long-term, competitive pressures, especially from biosimilars, are likely to substantially impact pricing, emphasizing the importance of strategic lifecycle management.


FAQs

1. What factors most significantly influence the pricing of NDC 51167-0400?
Manufacturers' patent status, market competition, reimbursement policies, therapeutic value, and regulatory approval pathways predominantly shape pricing dynamics.

2. How will biosimilar entry affect the market for this drug?
Biosimilar entry—anticipated within 8-10 years post-launch—will likely induce significant price reductions and market share shifts, though brand loyalty and pricing strategies can mitigate impacts.

3. Is the current price of this drug sustainable?
Yes, while high-priced biologics are justified by R&D costs and therapeutic value, long-term sustainability depends on market exclusivity, competition, and payer policies.

4. How can payers influence future pricing?
By negotiating formulary inclusion, implementing step therapy, and favoring biosimilars, payers can exert downward pressure on prices.

5. What growth opportunities exist for this drug?
Expanding indications, improving delivery methods, and securing favorable formulary status are key opportunities for growth and maintaining premium pricing.


Sources

[1] IQVIA Pharmaceutical Market Data 2022.
[2] SSR Health Insights 2022.
[3] FDA Labeling and Patent Data.
[4] Industry Reports on Biosimilar Market Trends 2022.

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