Efficacy and Pharmacogenomics of Salvage CLAG-M Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia
Recruiting
Medical College of Wisconsin
Phase 2
2017-06-14
This is a prospective phase II clinical study to be conducted at the Medical College of
Wisconsin. After meeting the study criteria and enrollment, patients will be treated with
Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) chemotherapy and followed at periodic
intervals to determine the primary and secondary objectives.
Evaluation of the Onset of Action in Highly Active MS (MAGNIFY)
Active, not recruiting
Merck KGaA, Darmstadt, Germany
Phase 4
2018-05-28
The main purpose of the study was to determine the onset of Mavenclad® action by frequent
magnetic resonance imaging (MRI) assessment of the combined unique active (CUA) lesions in
participants with highly active relapsing multiple sclerosis (MS).
Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)
Active, not recruiting
Merck KGaA, Darmstadt, Germany
Phase 4
2018-06-20
The main purpose of the study is to assess the health-related quality of life (HRQoL) through
the Multiple Sclerosis Quality of Life-54 Questionnaire (MSQoL-54) scale in highly-active
relapsing multiple sclerosis (RMS) subjects treated with Mavenclad® for 2 years (24 months).
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