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QuintilesIMS
Harvard Business School
Medtronic
Cipla
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AstraZeneca
Cerilliant
US Department of Justice
Accenture

Generated: July 23, 2018

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CLINICAL TRIALS PROFILE FOR FOSAPREPITANT DIMEGLUMINE

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Clinical Trials for fosaprepitant dimeglumine

Trial ID Title Status Sponsor Phase Summary
NCT00818259 A Study of MK-0869 (Aprepitant) and MK-0517 (Fosaprepitant) in Pediatric Participants Receiving Chemotherapy (MK-0869-134) Terminated Merck Sharp & Dohme Corp. Phase 1 This study will determine the appropriate dosing regimen of aprepitant and fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric participants from 0 months to 17 years of age.
NCT00895245 Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy Terminated National Cancer Institute (NCI) Phase 2 RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.
NCT00895245 Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy Terminated University of Washington Phase 2 RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.
NCT00945321 A Study to Assess the Bioequivalence of Aprepitant and Fosaprepitant and the Effect of Food on Aprepitant Bioavailability (0869-165) Completed Merck Sharp & Dohme Corp. Phase 1 This study will assess the bioequivalence of single oral doses of aprepitant (MK0869) to a single intravenous infusion of fosaprepitant (MK0517) and also determine the effect of food on the bioavailability of oral aprepitant.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for fosaprepitant dimeglumine

Condition Name

Condition Name for fosaprepitant dimeglumine
Intervention Trials
Chemotherapy-Induced Nausea and Vomiting 4
Vomiting 2
Nausea 2
Stage III Squamous Cell Carcinoma of the Larynx 1
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Condition MeSH

Condition MeSH for fosaprepitant dimeglumine
Intervention Trials
Vomiting 10
Nausea 7
Nasopharyngeal Neoplasms 1
Breast Neoplasms 1
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Clinical Trial Locations for fosaprepitant dimeglumine

Trials by Country

Trials by Country for fosaprepitant dimeglumine
Location Trials
United States 5
Germany 1
Denmark 1
Australia 1
Norway 1
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Trials by US State

Trials by US State for fosaprepitant dimeglumine
Location Trials
Oregon 1
Washington 1
California 1
Michigan 1
Texas 1
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Clinical Trial Progress for fosaprepitant dimeglumine

Clinical Trial Phase

Clinical Trial Phase for fosaprepitant dimeglumine
Clinical Trial Phase Trials
Phase 3 2
Phase 2 2
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for fosaprepitant dimeglumine
Clinical Trial Phase Trials
Completed 5
Terminated 3
Active, not recruiting 1
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Clinical Trial Sponsors for fosaprepitant dimeglumine

Sponsor Name

Sponsor Name for fosaprepitant dimeglumine
Sponsor Trials
Merck Sharp & Dohme Corp. 5
National Cancer Institute (NCI) 4
M.D. Anderson Cancer Center 1
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Sponsor Type

Sponsor Type for fosaprepitant dimeglumine
Sponsor Trials
Industry 6
Other 6
NIH 4
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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
McKesson
AstraZeneca
US Department of Justice
Accenture
Fish and Richardson
Deloitte
McKinsey
Farmers Insurance

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