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Federal Trade Commission
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Generated: April 20, 2018

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CLINICAL TRIALS PROFILE FOR ERYTHROMYCIN ETHYLSUCCINATE; SULFISOXAZOLE ACETYL

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Clinical Trials for erythromycin ethylsuccinate; sulfisoxazole acetyl

Trial ID Title Status Sponsor Phase Summary
NCT00000120 Clinical Trial of Eye Prophylaxis in the Newborn Completed National Eye Institute (NEI) Phase 3 To compare the effectiveness of silver nitrate drops, erythromycin ointment, or no medication in preventing neonatal conjunctivitis caused by Chlamydia trachomatis and other eye infections. To compare side effects of the two prophylactic agents.
NCT00002194 An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4. Completed Boehringer Ingelheim Phase 1 To evaluate the potential pharmacokinetic interaction between nevirapine and clarithromycin, and to determine the effects of nevirapine on cytochrome P450 3A4 (CYP3A4) activity in vivo.
NCT00004564 The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A Unknown status National Center for Research Resources (NCRR) N/A The objective of this study is to determine if the action of the drug called clopidogrel, that you will start taking, will be decreased by another drug called atorvastatin, that you will also start taking. Clopidogrel is an oral antiplatelet agent that has been shown to prevent strokes and heart attacks. Atorvastatin is a cholesterol lowering agent. Twenty adults 18-75 years of age requiring cholesterol-lowering agent and antiplatelet agent therapy will be recruited for this study during their cardiology clinic visitation. In one group, antiplatelet agent (clopidogrel) regimen will be administered first, then followed by cholesterol-lowering medication (atorvastatin). In the second group, atorvastatin will be administered first, followed by clopidogrel. A new test called the erythromycin breath test will be administered to you three times during the study to measure how your liver will metabolize these drugs. Blood samples will also be obtained to assess platelet function. The criteria for exclusion are patient refusal or inability to give written consent, patients with allergic reaction to erythromycin, patients with known bleeding problems, liver disease, significant lung disease kidney disease and pregnancy. Patients with psychiatric impairment and documented history of substance abuse will also be excluded from the study.
NCT00005624 CI-994 in Treating Patients With Advanced Myeloma Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CI-994 in treating patients who have advanced myeloma.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for erythromycin ethylsuccinate; sulfisoxazole acetyl

Condition Name

Condition Name for erythromycin ethylsuccinate; sulfisoxazole acetyl
Intervention Trials
Healthy 15
HIV Infections 6
Multiple Myeloma 5
Bipolar Disorder 5
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Condition MeSH

Condition MeSH for erythromycin ethylsuccinate; sulfisoxazole acetyl
Intervention Trials
Syndrome 15
Kidney Diseases 11
Diabetes Mellitus 9
Depression 8
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Clinical Trial Locations for erythromycin ethylsuccinate; sulfisoxazole acetyl

Trials by Country

Trials by Country for erythromycin ethylsuccinate; sulfisoxazole acetyl
Location Trials
United States 222
Japan 47
Canada 22
Italy 21
Brazil 18
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Trials by US State

Trials by US State for erythromycin ethylsuccinate; sulfisoxazole acetyl
Location Trials
Maryland 21
California 18
Minnesota 12
New York 12
Texas 11
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Clinical Trial Progress for erythromycin ethylsuccinate; sulfisoxazole acetyl

Clinical Trial Phase

Clinical Trial Phase for erythromycin ethylsuccinate; sulfisoxazole acetyl
Clinical Trial Phase Trials
Phase 4 72
Phase 3 44
Phase 2/Phase 3 6
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Clinical Trial Status

Clinical Trial Status for erythromycin ethylsuccinate; sulfisoxazole acetyl
Clinical Trial Phase Trials
Completed 164
Recruiting 50
Unknown status 32
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Clinical Trial Sponsors for erythromycin ethylsuccinate; sulfisoxazole acetyl

Sponsor Name

Sponsor Name for erythromycin ethylsuccinate; sulfisoxazole acetyl
Sponsor Trials
National Institute of Mental Health (NIMH) 8
AstraZeneca 6
University of Catania 6
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Sponsor Type

Sponsor Type for erythromycin ethylsuccinate; sulfisoxazole acetyl
Sponsor Trials
Other 322
Industry 84
NIH 42
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Serving hundreds of leading biopharmaceutical companies globally:

US Army
US Department of Justice
Julphar
QuintilesIMS
Baxter
Mallinckrodt
Queensland Health
Cipla
McKinsey

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