GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Feasibility Trial
Not yet recruiting
Vanderbilt University Medical Center
Phase 2
2024-10-01
The goal of this pilot clinical trial is to determine the effectiveness of Tirzepatide in
patients with persistent obesity (BMI > 30) 12 months after bariatric surgery (Roux-en-Y
Gastric Bypass). The investigators also aim to determine the frequency of side effects with
Tirzepatide in this patient population. Patients who take tirzepatide 12 months after
bariatric surgery will be compared to patients who receive a placebo.
Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients
RECRUITING
University of Miami
PHASE4
2025-03-05
The purpose of this study is to use diet and an injectable medication called tirzepatide (Zepbound) glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist (GIP-GLP-1 RA) medication as adjunctive therapy (another treatment used together with the primary treatment) for Crohn's disease patients with mild disease who are on stable doses of biologic medication (infliximab or adalimumab) and who have a body mass index (BMI) of at least 27.
The goal of this study is to determine whether a medicine called tirzepatide, also called Zepbound, can reduce symptoms of Long COVID. A randomized control trial will allow us to measure the effect of the treatment by having half of the participants take the medication and half take a placebo that has no medication. Participants will take the medication (or placebo) they are given and complete study surveys for 12 months. All of the study tasks are done remotely from the comfort of a participants home.
The goal of this study is to determine whether a medicine called tirzepatide, also called Zepbound, can reduce symptoms of Long COVID. A randomized control trial will allow us to measure the effect of the treatment by having half of the participants take the medication and half take a placebo that has no medication. Participants will take the medication (or placebo) they are given and complete study surveys for 12 months. All of the study tasks are done remotely from the comfort of a participants home.
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