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Last Updated: December 12, 2024

CLINICAL TRIALS PROFILE FOR TROSPIUM CHLORIDE


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All Clinical Trials for Trospium Chloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00465959 ↗ Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease Completed Alkermes, Inc. Phase 1/Phase 2 2007-04-01 To assess the effect of a single dose of TrIP on pulmonary function in patients with COPD
NCT00465959 ↗ Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease Completed Endo Pharmaceuticals Phase 1/Phase 2 2007-04-01 To assess the effect of a single dose of TrIP on pulmonary function in patients with COPD
NCT00800462 ↗ Comparative Study of the Efficacy and Safety of Muscarinic M3 Receptors Antagonists in the Treatment of Neurogenic Detrusor Overactivity Completed Ontario Neurotrauma Foundation Phase 4 2008-03-01 This is a phase IV, double-blind, multicenter, randomized trial evaluating the efficacy and safety of two M3 receptors antagonists (Trospium Chloride and Darifenacin Hydrobromide) with one standard drug (Oxybutynin Chloride) for treatment of overactive bladder in individuals with spinal cord injury.
NCT00800462 ↗ Comparative Study of the Efficacy and Safety of Muscarinic M3 Receptors Antagonists in the Treatment of Neurogenic Detrusor Overactivity Completed Toronto Rehabilitation Institute Phase 4 2008-03-01 This is a phase IV, double-blind, multicenter, randomized trial evaluating the efficacy and safety of two M3 receptors antagonists (Trospium Chloride and Darifenacin Hydrobromide) with one standard drug (Oxybutynin Chloride) for treatment of overactive bladder in individuals with spinal cord injury.
NCT00863551 ↗ Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial Completed Allergan Phase 4 2009-04-01 This study evaluates the penetration through the blood-brain-barrier of trospium chloride at plasma steady state (Day 10) in elderly subjects with overactive bladder symptoms. Trospium levels in cerebrospinal fluid (CSF) and peak and trough plasma levels will be measured. Baseline and day 10 post-dose neurocognitive testing will be compared using a reliable change index to assess if any study subject shows evidence of a clinically and statistically significant change in memory.
NCT00932022 ↗ Trospium Chloride XR in Obese Female Patients With Overactive Bladder Completed Allergan Phase 4 2009-07-01 This study evaluated the effectiveness of trospium chloride extended release (XR) in obese female patients with overactive bladder (OAB). Patients received either placebo and trospium chloride XR or placebo only. The study assessed the change from baseline in urinary frequency, urgency, and incontinence for trospium chloride XR versus a placebo-pill. The study was 14 weeks in duration.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Trospium Chloride

Condition Name

Condition Name for Trospium Chloride
Intervention Trials
Schizophrenia 8
Overactive Bladder 5
Schizophrenia; Psychosis 2
Intestinal Obstruction 2
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Condition MeSH

Condition MeSH for Trospium Chloride
Intervention Trials
Urinary Bladder, Overactive 8
Schizophrenia 8
Enuresis 2
Intestinal Obstruction 2
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Clinical Trial Locations for Trospium Chloride

Trials by Country

Trials by Country for Trospium Chloride
Location Trials
United States 68
Germany 2
Canada 2
Ukraine 2
Egypt 1
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Trials by US State

Trials by US State for Trospium Chloride
Location Trials
California 10
Texas 7
Ohio 6
New Jersey 5
Georgia 5
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Clinical Trial Progress for Trospium Chloride

Clinical Trial Phase

Clinical Trial Phase for Trospium Chloride
Clinical Trial Phase Trials
Phase 4 6
Phase 3 7
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Trospium Chloride
Clinical Trial Phase Trials
Completed 13
Recruiting 7
Not yet recruiting 1
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Clinical Trial Sponsors for Trospium Chloride

Sponsor Name

Sponsor Name for Trospium Chloride
Sponsor Trials
Karuna Therapeutics 8
Allergan 5
Karuna Pharmaceuticals 4
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Sponsor Type

Sponsor Type for Trospium Chloride
Sponsor Trials
Industry 19
Other 10
NIH 3
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