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Last Updated: April 25, 2024

CLINICAL TRIALS PROFILE FOR RIOCIGUAT


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All Clinical Trials for Riociguat

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00855660 ↗ Effect of Riociguat on Bone Metabolism Completed Bayer Phase 1 2009-03-01 Investigation of the effect of Riociguat, administered as 2.5 mg IR-tablets TID over 14 days, on bone metabolism.
NCT01014247 ↗ Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation Completed Bayer Phase 1 2009-11-01 The aim of this study is to investigate the effect of moxifloxacin on the QT interval in order to gain information on the validity of results that will be collected during another clinical study testing riociguat in patients with pulmonary arterial hypertension (PATENT-1 study).
NCT01065051 ↗ Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics Terminated Bayer Phase 2 2010-11-01 The aim of this study is to assess whether oral Riociguat affects the left ventricular contractility and relaxation in patients with pulmonary hypertension associated with left ventricular systolic dysfunction
NCT01065454 ↗ A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction Active, not recruiting Bayer Phase 2 2010-04-14 The aim of this study is to assess whether increasing oral doses of Riociguat are safe and improve the well-being, symptoms and outcome in patients with pulmonary hypertension associated with left ventricular systolic dysfunction
NCT01165931 ↗ Coronary Vasomotor Response After Riociguat Exposure Withdrawn Bayer Phase 2 2012-05-01 The aim of the study is to assess the effects of intracoronary Riociguat on coronary blood flow in subjects with coronary artery disease and to compare this effect with the intracoronary nitroglycerin, a coronary vasodilator widly used to treat patients with coronary artery disease.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Riociguat

Condition Name

Condition Name for Riociguat
Intervention Trials
Hypertension, Pulmonary 13
Chronic Thromboembolic Pulmonary Hypertension 5
Pulmonary Arterial Hypertension 3
Ventricular Dysfunction, Left 3
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Condition MeSH

Condition MeSH for Riociguat
Intervention Trials
Hypertension 25
Hypertension, Pulmonary 24
Familial Primary Pulmonary Hypertension 9
Pulmonary Arterial Hypertension 9
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Clinical Trial Locations for Riociguat

Trials by Country

Trials by Country for Riociguat
Location Trials
United States 143
Germany 71
Japan 39
Italy 28
United Kingdom 26
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Trials by US State

Trials by US State for Riociguat
Location Trials
Massachusetts 10
New York 9
California 9
Ohio 9
Pennsylvania 9
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Clinical Trial Progress for Riociguat

Clinical Trial Phase

Clinical Trial Phase for Riociguat
Clinical Trial Phase Trials
Phase 4 7
Phase 3 5
Phase 2/Phase 3 1
[disabled in preview] 26
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Clinical Trial Status

Clinical Trial Status for Riociguat
Clinical Trial Phase Trials
Completed 18
Recruiting 15
Not yet recruiting 5
[disabled in preview] 7
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Clinical Trial Sponsors for Riociguat

Sponsor Name

Sponsor Name for Riociguat
Sponsor Trials
Bayer 27
Actelion 4
Merck Sharp & Dohme Corp. 4
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Sponsor Type

Sponsor Type for Riociguat
Sponsor Trials
Industry 37
Other 28
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