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Generated: December 10, 2018

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CLINICAL TRIALS PROFILE FOR REPAGLINIDE

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Clinical Trials for Repaglinide

Trial ID Title Status Sponsor Phase Summary
NCT00072904 Diabetes Therapy to Improve BMI and Lung Function in CF Completed Cystic Fibrosis Foundation Therapeutics Phase 3 To recruit 150 adult patients with cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia for a multi-center, twelve month, placebo-controlled intervention trial testing the ability of insulin or repaglinide to improve body mass index (BMI) and stabilize pulmonary function in cystic fibrosis (CF).
NCT00072904 Diabetes Therapy to Improve BMI and Lung Function in CF Completed Novo Nordisk A/S Phase 3 To recruit 150 adult patients with cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia for a multi-center, twelve month, placebo-controlled intervention trial testing the ability of insulin or repaglinide to improve body mass index (BMI) and stabilize pulmonary function in cystic fibrosis (CF).
NCT00072904 Diabetes Therapy to Improve BMI and Lung Function in CF Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Phase 3 To recruit 150 adult patients with cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia for a multi-center, twelve month, placebo-controlled intervention trial testing the ability of insulin or repaglinide to improve body mass index (BMI) and stabilize pulmonary function in cystic fibrosis (CF).
NCT00118950 Effect of Metformin Versus Repaglinide Treatment in Non-Obese Type 2 Diabetic Patients Uncontrolled by Diet Completed Steno Diabetes Center Phase 4 Background: Metformin is the first drug of choice in obese patients with type-2 diabetes (T2DM) due to its antiglycaemic as well as its cardiovascular protective potentials. In non-obese T2DM patients insulin-secretagogues are empirically used as first choice. The aim of this study was to evaluate the effect of metformin versus an insulin-secretagogue, repaglinide on glycaemic regulation and non-glycaemic cardiovascular risk markers in non-obese patients with T2DM. Methods: Single-center, randomised, double-masked, double-dummy, cross-over-study of 96 non-obese (BMI ≤ 27 kg/m2) Caucasian T2DM-patients. After a one month run-in on diet-only treatment, patients were randomised to either repaglinide 2mg three times a day (t.i.d). followed by metformin 1g twice a day (b.i.d.) or vice versa each for a period of four months with a one month wash-out between interventions.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Repaglinide

Condition Name

Condition Name for Repaglinide
Intervention Trials
Diabetes Mellitus, Type 2 30
Diabetes 23
Type 2 Diabetes Mellitus 4
Healthy Subjects 2
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Condition MeSH

Condition MeSH for Repaglinide
Intervention Trials
Diabetes Mellitus 38
Diabetes Mellitus, Type 2 36
Fibrosis 4
Cystic Fibrosis 4
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Clinical Trial Locations for Repaglinide

Trials by Country

Trials by Country for Repaglinide
Location Trials
United States 48
China 17
South Africa 5
Canada 4
Denmark 3
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Trials by US State

Trials by US State for Repaglinide
Location Trials
Pennsylvania 3
Texas 3
Maryland 2
Georgia 2
Arizona 2
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Clinical Trial Progress for Repaglinide

Clinical Trial Phase

Clinical Trial Phase for Repaglinide
Clinical Trial Phase Trials
Phase 4 20
Phase 3 4
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Repaglinide
Clinical Trial Phase Trials
Completed 39
Recruiting 3
Unknown status 2
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Clinical Trial Sponsors for Repaglinide

Sponsor Name

Sponsor Name for Repaglinide
Sponsor Trials
Novo Nordisk A/S 27
Canadian Institutes of Health Research (CIHR) 3
Canadian Network for Observational Drug Effect Studies, CNODES 3
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Sponsor Type

Sponsor Type for Repaglinide
Sponsor Trials
Industry 36
Other 30
NIH 2
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Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
Healthtrust
QuintilesIMS
McKesson
Citi
McKinsey
Johnson and Johnson
Argus Health
Harvard Business School

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