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CLINICAL TRIALS PROFILE FOR OXYCODONE HYDROCHLORIDE

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Clinical Trials for Oxycodone Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00000273	A Laboratory Model for Heroin Abuse Medications - 8	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."
NCT00000273	A Laboratory Model for Heroin Abuse Medications - 8	Completed	New York State Psychiatric Institute	Phase 2	The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."
NCT00027014	Herb-Opioid Interactions	Completed	National Center for Complementary and Integrative Health (NCCIH)	Phase 4	This is a series of studies in healthy volunteers to assess the potential for adverse interactions between St. John's wort (SJW) extract and two narcotic (opioid) pain medications: oxycodone and fentanyl. In the case of oxycodone, we are interested in whether SJW treatment promotes the metabolism of oxycodone, such that it lowers the effectiveness of standard doses of oxycodone in treating pain problems. For the fentanyl study, we will investigate whether SJW treatment will interfere with the delivery of fentanyl to the brain and diminish it's effectiveness to relieve pain. There is evidence to suggest that SJW treatment may increase the activity of a transporter protein, named P-glycoprotein (Pgp), in the blood-brain barrier (BBB) that protects the brain from exposure to drugs and other dietary and environmental toxins.
NCT00092313	A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182)	Completed	Merck Sharp & Dohme Corp.	Phase 3	The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

Clinical Trial Conditions for Oxycodone Hydrochloride

Condition Name

Condition Name for Oxycodone Hydrochloride
Intervention	Trials
Pain	80
Postoperative Pain	31
Pain, Postoperative	30
Healthy	29

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Condition MeSH

Condition MeSH for Oxycodone Hydrochloride
Intervention	Trials
Pain, Postoperative	88
Back Pain	29
Osteoarthritis	26
Low Back Pain	26

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Clinical Trial Locations for Oxycodone Hydrochloride

Trials by Country

Trials by Country for Oxycodone Hydrochloride
Location	Trials
United States	882
China	28
Canada	24
Finland	19
Italy	17

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Trials by US State

Trials by US State for Oxycodone Hydrochloride
Location	Trials
New York	60
California	50
Texas	48
Pennsylvania	44
Florida	36

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Clinical Trial Progress for Oxycodone Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Oxycodone Hydrochloride
Clinical Trial Phase	Trials
Phase 4	134
Phase 3	98
Phase 2/Phase 3	4

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Clinical Trial Status

Clinical Trial Status for Oxycodone Hydrochloride
Clinical Trial Phase	Trials
Completed	210
Recruiting	73
Not yet recruiting	60

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Clinical Trial Sponsors for Oxycodone Hydrochloride

Sponsor Name

Sponsor Name for Oxycodone Hydrochloride
Sponsor	Trials
Purdue Pharma LP	23
Grünenthal GmbH	19
Pfizer	17

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Sponsor Type

Sponsor Type for Oxycodone Hydrochloride
Sponsor	Trials
Other	305
Industry	210
NIH	21

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