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CLINICAL TRIALS PROFILE FOR NICORETTE

Clinical Trials for Nicorette

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00139516	Chinese Community Smoking Cessation Project	Completed	National Heart, Lung, and Blood Institute (NHLBI)	N/A	The study has two objectives/aims: Aim 1: To test the efficacy of the intervention among adult smokers with cardiovascular disease, pulmonary disease and diabetes mellitus related illnesses (later modified to Chinese adults with and without diseases); and Aim 2: To examine a set of measures (background, general health, psychosocial, and smoking process) that are associated with smoking cessation at 6 and 12 months
NCT00139516	Chinese Community Smoking Cessation Project	Completed	University of California, San Francisco	N/A	The study has two objectives/aims: Aim 1: To test the efficacy of the intervention among adult smokers with cardiovascular disease, pulmonary disease and diabetes mellitus related illnesses (later modified to Chinese adults with and without diseases); and Aim 2: To examine a set of measures (background, general health, psychosocial, and smoking process) that are associated with smoking cessation at 6 and 12 months
NCT00158171	Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	Currently one in five high school students smokes. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems. This study will compare the effectiveness of treatment with bupropion, a nicotine patch, or nicotine gum in supporting the reduction of smoking in adolescent smokers.
NCT00174499	A Pilot Drug Trial That Evaluates the Whitening Potential of Nicotine Gum	Completed	McNeil AB	Phase 4	The purpose of this research study is to evaluate the effects on existing tooth stain of nicotine gum. The study will enroll adults who have visible tooth staining.
NCT00176449	A Comparison of Bupropion SR and Placebo for Smoking Cessation	Completed	VA Office of Research and Development	Phase 4	The purpose of this study is to examine whether the adjunctive use of bupropion SR in the context of a psychoeducational program modified for people with schizophrenia might improve the likelihood of successful abstinence in this population. If bupropion SR is effective for reducing cigarette smoking, then it will be important to determine if decreased nicotine intake is associated with a worsening of psychotic, anxiety or depressive symptoms. In addition, it would be important to determine the effect that a reduction in nicotine stimulation would have on patient's cognitive functioning, as nicotinic receptors have been shown to regulate attention and memory function, and it is hypothesized that these functions are normalized by acute nicotine administration in people with schizophrenia
NCT00176449	A Comparison of Bupropion SR and Placebo for Smoking Cessation	Completed	University of Maryland	Phase 4	The purpose of this study is to examine whether the adjunctive use of bupropion SR in the context of a psychoeducational program modified for people with schizophrenia might improve the likelihood of successful abstinence in this population. If bupropion SR is effective for reducing cigarette smoking, then it will be important to determine if decreased nicotine intake is associated with a worsening of psychotic, anxiety or depressive symptoms. In addition, it would be important to determine the effect that a reduction in nicotine stimulation would have on patient's cognitive functioning, as nicotinic receptors have been shown to regulate attention and memory function, and it is hypothesized that these functions are normalized by acute nicotine administration in people with schizophrenia
Trial ID	Title	Status	Sponsor	Phase	Summary