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Generated: November 17, 2018

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CLINICAL TRIALS PROFILE FOR MINOXIDIL (FOR MEN)

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Clinical Trials for Minoxidil (for Men)

Trial ID Title Status Sponsor Phase Summary
NCT00007592 Hypertension Screening and Treatment Program Completed VA Office of Research and Development N/A Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00151515 A Study to Evaluate the Effectiveness and Safety of 5 Percent Minoxidil Foam in the Treatment of Male Pattern Hair Loss Completed Johnson & Johnson Consumer and Personal Products Worldwide Phase 3 The primary purpose of the study is to evaluate the efficacy of a topical 5% minoxidil formulation in males for the treatment of pattern hair loss. The secondary purpose is to evaluate the safety of a topical 5% minoxidil formulation in males when used twice daily for the treatment of pattern hair loss and to obtain the safety data on the investigational product when used twice daily for up to one year.
NCT00175617 Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss Unknown status University of British Columbia Phase 2 This study evaluates the efficacy of therapy with the anti-androgen spironolactone compared to topical minoxidil in female pattern hair loss.
NCT00418730 Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss Completed Neosil, Inc. Phase 2 The purpose of this study is to measure the hair growth response to topical NEOSH101 when applied twice daily to the balding scalp for 16 weeks. One hundred eighty men with Norwood/Hamilton grades III-IV with thinning in the top and center of the scalp will participate. Three equally sized treatment groups (60 men each) will receive either topical NEOSH101 2.0%, minoxidil 5%, or placebo.
NCT00607477 Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension Terminated University of Chicago N/A The purpose of this study is to describe the length of time and extent of blood pressure response to minoxidil and hydralazine among cancer patients with difficult-to-treat vascular endothelial growth factor (VEGF) inhibitor treatment induced hypertension.
NCT00876200 Efficacy of Minoxidil in Children With Williams-Beuren Syndrome Completed Hospices Civils de Lyon Phase 2 The Williams-Beuren syndrome (WBS) is a sporadic congenital disorder characterized by a multisystem developmental impairment. This syndrome is caused by a microdeletion in chromosome 7q11.23 that encompasses loss of the elastin locus. Elastin, which is part of the extracellular matrix, controls proliferation of vascular smooth muscle cells (VSMCs) and stabilizes arterial structure. Loss of elastin gene in WBS patients has been claimed to provide a biological basis for the abnormal elastic fibre properties leading to cardiovascular abnormalities like supravalvular aortic stenosis (SVAS), hypertension, arteriosclerosis and stenosis in more than 50% of WBS children. These cardiovascular pathologies result in important consequences and neither curative nor preventive medicinal treatments exist at this time. Surgery is needed in more than half cases, while it is often leading to complications. Minoxidil is a well-known antihypertensive drug used in adults and children. Furthermore, according to animal studies, minoxidil seems to increase arterial elastin content by decreasing elastase activity in these tissues. Other data demonstrate that minoxidil specifically stimulate elastin synthesis. Working Hypothesis:If insufficient elastin synthesis leads to vascular complications and arterial hypertension in children with WBS, restoration of sufficient quantity of elastin should then result in prevention or inhibition of vascular malformations and improvement in arterial tension. Therefore, as a pharmacological agent capable to stimulate elastin expression, minoxidil might be a useful drug for the treatment of abnormal elastin metabolism in WBS children. Objective:To evaluate the efficacy of minoxidil on cardiovascular structure in children with Williams Beuren syndrome. Methodology: randomized controlled trial on two parallel group (23 patients in each arm) Main criterion:variation of carotid Intima-media thickness (IMT) before and after 12 months of treatment with Minoxidil versus placebo Secondary intermediate criteria of the vascular properties are arterial stiffness, cardiac and renal stenosis, arterial tension. Total study duration:30 months including a 12 month-recruitment period
NCT00958750 Efficacy and Safety Study to Compare Two Minoxidil Formulations on Women With Androgenetic Alopecia Completed Charite University, Berlin, Germany Phase 3 The purpose of this study is to determine in women the risk/benefit profile and non-inferiority of a topical 5% Minoxidil foam formulation applied once daily for the treatment of androgenetic alopecia in comparison to 2% MTS used twice daily, using objective and subjective efficacy measures and safety assessments for a study period of 24 weeks.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Minoxidil (for Men)

Condition Name

Condition Name for Minoxidil (for Men)
Intervention Trials
Androgenetic Alopecia 11
Female Pattern Hair Loss 5
Alopecia 5
Alopecia Areata 3
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Condition MeSH

Condition MeSH for Minoxidil (for Men)
Intervention Trials
Alopecia 27
Alopecia Areata 25
Hypotrichosis 2
Hypertension 2
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Clinical Trial Locations for Minoxidil (for Men)

Trials by Country

Trials by Country for Minoxidil (for Men)
Location Trials
United States 51
Germany 7
Thailand 6
France 5
Italy 3
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Trials by US State

Trials by US State for Minoxidil (for Men)
Location Trials
Texas 6
Minnesota 4
Ohio 4
California 4
Oregon 4
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Clinical Trial Progress for Minoxidil (for Men)

Clinical Trial Phase

Clinical Trial Phase for Minoxidil (for Men)
Clinical Trial Phase Trials
Phase 4 8
Phase 3 7
Phase 2 9
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Clinical Trial Status

Clinical Trial Status for Minoxidil (for Men)
Clinical Trial Phase Trials
Completed 21
Unknown status 5
Not yet recruiting 3
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Clinical Trial Sponsors for Minoxidil (for Men)

Sponsor Name

Sponsor Name for Minoxidil (for Men)
Sponsor Trials
Mae Fah Luang University Hospital 5
Galderma Laboratories, L.P. 2
Siriraj Hospital 2
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Sponsor Type

Sponsor Type for Minoxidil (for Men)
Sponsor Trials
Other 30
Industry 16
U.S. Fed 1
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