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Last Updated: October 21, 2019

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CLINICAL TRIALS PROFILE FOR METHYL AMINOLEVULINATE HYDROCHLORIDE

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Clinical Trials for Methyl Aminolevulinate Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00369018 A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions. Completed Photocure Phase 1/Phase 2 2006-08-01 The study will determine the best drug (MAL or HAL) dosage for photodynamic therapy of cervical precancerous lesions (dysplasia) in women that are referred for conisation (surgery).
NCT00535080 Compassionate Use of Metvix® (Methyl Aminolevulinate) Photodynamic Therapy (PDT) in Subjects With Field Actinic Keratoses, Large/Multiple Superficial Basal Cell Carcinomas (BCCs), or Bowen's Disease No longer available Galderma N/A 1969-12-31 The aim of this study is to provide this investigational drug to patients who cannot be optimally treated with conventional therapies and to collect efficacy and safety data on the use of Metvix PDT in subjects with field actinic keratoses, large/multiple superficial basal cell carcinomas (BCCs) or Bowen's disease.
NCT00594425 Photodynamic Therapy (PDT) With Methyl Aminolevulinate (MAL) Cream in Moderate to Severe Acne Completed Photocure Phase 2 2007-02-01 This multicenter study will be divided into 2 phases. The first phase will be an open label, dose-escalation phase, while the second will be a blinded, randomized, vehicle-controlled, parallel-group, dose-response phase. The second phase will only start if the first phase succeeds in establishing well tolerated dose(s). Patients with moderate to severe acne vulgaris in the face will be included.The results from part 2 has been presented in the result section.
NCT00629317 Trial of Methyl Aminolevulinate Plus Aktilite in Facial Photodamage Completed Galderma Phase 3 2008-02-01 The aim of the study is to determine the efficacy of MAL + Aktilite versus placebo + Aktilite in facial photodamage in a randomized double blind trial.
NCT00629317 Trial of Methyl Aminolevulinate Plus Aktilite in Facial Photodamage Completed Universidad de Antioquia Phase 3 2008-02-01 The aim of the study is to determine the efficacy of MAL + Aktilite versus placebo + Aktilite in facial photodamage in a randomized double blind trial.
NCT00673933 Photodynamic Therapy (PDT) With Methyl Aminolevulinate (MAL) Cream in Patients With Skin Type V or IV With Acne Vulgaris Completed Photocure Phase 2 2008-05-01 In this multicenter study, patients with dark skin and acne vulgaris will be included. The patients will receive treatment with MAL PDT and placebo PDT.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Methyl Aminolevulinate Hydrochloride

Condition Name

Condition Name for Methyl Aminolevulinate Hydrochloride
Intervention Trials
Actinic Keratosis 6
Bowen's Disease 4
Acne Vulgaris 2
Superficial Basal Cell Carcinoma 2
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Condition MeSH

Condition MeSH for Methyl Aminolevulinate Hydrochloride
Intervention Trials
Keratosis, Actinic 9
Keratosis 9
Carcinoma, Basal Cell 5
Carcinoma 4
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Clinical Trial Locations for Methyl Aminolevulinate Hydrochloride

Trials by Country

Trials by Country for Methyl Aminolevulinate Hydrochloride
Location Trials
United States 15
Colombia 2
Netherlands 2
Norway 2
Korea, Republic of 2
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Trials by US State

Trials by US State for Methyl Aminolevulinate Hydrochloride
Location Trials
New York 2
New Mexico 2
Illinois 2
California 2
District of Columbia 1
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Clinical Trial Progress for Methyl Aminolevulinate Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Methyl Aminolevulinate Hydrochloride
Clinical Trial Phase Trials
Phase 4 5
Phase 3 1
Phase 2 6
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Clinical Trial Status

Clinical Trial Status for Methyl Aminolevulinate Hydrochloride
Clinical Trial Phase Trials
Completed 14
Recruiting 4
Not yet recruiting 2
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Clinical Trial Sponsors for Methyl Aminolevulinate Hydrochloride

Sponsor Name

Sponsor Name for Methyl Aminolevulinate Hydrochloride
Sponsor Trials
Dong-A University 4
Photocure 4
Maastricht University Medical Center 2
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Sponsor Type

Sponsor Type for Methyl Aminolevulinate Hydrochloride
Sponsor Trials
Other 35
Industry 8
NIH 1
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