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Last Updated: November 4, 2024

CLINICAL TRIALS PROFILE FOR METADATE CD


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All Clinical Trials for Metadate Cd

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00301639 ↗ A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults Completed McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. Phase 3 2005-03-01 The specific aim of this study is to document the pharmacokinetics of dopamine transporter DAT receptor occupancy of OROS MPH and Metadate CD using PET scanning with C-11 Altropane as the ligand. We hypothesize that CNS DAT occupancy of OROS MPH will be greater than that of Metadate CD at 10 hours after administration.
NCT00301639 ↗ A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults Completed Massachusetts General Hospital Phase 3 2005-03-01 The specific aim of this study is to document the pharmacokinetics of dopamine transporter DAT receptor occupancy of OROS MPH and Metadate CD using PET scanning with C-11 Altropane as the ligand. We hypothesize that CNS DAT occupancy of OROS MPH will be greater than that of Metadate CD at 10 hours after administration.
NCT00381758 ↗ The COMACS Study: A Comparison of Methylphenidates in an Analog Classroom Setting Completed UCB Pharma Phase 4 2002-05-01 This study was designed to compare Concerta Extended Release tablets with Metadate CD capsules in children with ADHD who were between 6 and 12 years old. The effects on ADHD symptoms, and any side effects of treatment, were measured for 12 hours after dosing in a simulated classroom. The treatments were blinded and the effects were compared with a Placebo.
NCT01100658 ↗ Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors Terminated Children's Cancer Research Fund United States N/A 2010-05-01 While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention deficits in this population. Numerous studies have examined the effectiveness of methylphenidate in the treatment of children with attention deficit hyperactivity disorder (ADHD). However, the effectiveness of this medication for improving attention and behavioral functioning in children with medical illnesses or brain injury are less clear. Patients will be randomized to receive one week of Metadate CD (a controlled release form of methylphenidate, similar to Ritalin) and one week of placebo in a double-blind fashion.
NCT01100658 ↗ Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors Terminated University of Minnesota N/A 2010-05-01 While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention deficits in this population. Numerous studies have examined the effectiveness of methylphenidate in the treatment of children with attention deficit hyperactivity disorder (ADHD). However, the effectiveness of this medication for improving attention and behavioral functioning in children with medical illnesses or brain injury are less clear. Patients will be randomized to receive one week of Metadate CD (a controlled release form of methylphenidate, similar to Ritalin) and one week of placebo in a double-blind fashion.
NCT01100658 ↗ Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors Terminated University of Minnesota - Clinical and Translational Science Institute N/A 2010-05-01 While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention deficits in this population. Numerous studies have examined the effectiveness of methylphenidate in the treatment of children with attention deficit hyperactivity disorder (ADHD). However, the effectiveness of this medication for improving attention and behavioral functioning in children with medical illnesses or brain injury are less clear. Patients will be randomized to receive one week of Metadate CD (a controlled release form of methylphenidate, similar to Ritalin) and one week of placebo in a double-blind fashion.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Metadate Cd

Condition Name

Condition Name for Metadate Cd
Intervention Trials
Attention Deficit Hyperactivity Disorder 3
Lymphoblastic Leukemia, Acute, L1 1
Leukemia, Lymphoblastic, Acute 1
Lymphoblastic Leukemia, Acute, L2 1
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Condition MeSH

Condition MeSH for Metadate Cd
Intervention Trials
Attention Deficit Disorder with Hyperactivity 4
Hyperkinesis 2
Problem Behavior 1
Precursor Cell Lymphoblastic Leukemia-Lymphoma 1
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Clinical Trial Locations for Metadate Cd

Trials by Country

Trials by Country for Metadate Cd
Location Trials
United States 4
Korea, Republic of 1
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Trials by US State

Trials by US State for Metadate Cd
Location Trials
Kentucky 1
Iowa 1
Minnesota 1
Massachusetts 1
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Clinical Trial Progress for Metadate Cd

Clinical Trial Phase

Clinical Trial Phase for Metadate Cd
Clinical Trial Phase Trials
Phase 4 2
Phase 3 1
N/A 2
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Clinical Trial Status

Clinical Trial Status for Metadate Cd
Clinical Trial Phase Trials
Completed 3
Terminated 1
Unknown status 1
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Clinical Trial Sponsors for Metadate Cd

Sponsor Name

Sponsor Name for Metadate Cd
Sponsor Trials
Matthew J O'Brien, PhD, BCBA-D 1
Matthew O'Brien 1
National Institute on Drug Abuse (NIDA) 1
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Sponsor Type

Sponsor Type for Metadate Cd
Sponsor Trials
Other 8
Industry 3
NIH 1
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