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Last Updated: October 18, 2019

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CLINICAL TRIALS PROFILE FOR MESALAMINE

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Clinical Trials for Mesalamine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00063414 ISIS 2302-CS22, A 6-Week, Active-Controlled Clinical Study to Evaluate the Effectiveness of Alicaforsen (ISIS 2302) in Patients With Mild to Moderate Active Ulcerative Colitis Completed Ionis Pharmaceuticals, Inc. Phase 2 1969-12-31 This is a multi-center trial to test the safety, efficacy and tolerability of alicaforsen (ISIS 2302), a new type of drug called an antisense drug, in patients with mild to moderate active Ulcerative Colitis (UC). Alicaforsen is designed to reduce the production of a specific protein, called ICAM-1, a substance that plays a significant role in the increase of inflammation and is likely to be involved in inflammatory bowel diseases such as ulcerative colitis. The ISIS 2302-CS22 study will examine the effects of one of two dosages of alicaforsen delivered by enema over a six-week period as compared to an active control, mesalamine enema (The probability of receiving the alicaforsen formulation is 2:1). The primary objective of this study is to evaluate the percentage reduction in DAI at Week 6.
NCT00098111 Imuran (Azathioprine) Dose-Ranging Study in Crohn's Disease Terminated Massachusetts General Hospital Phase 3 2005-04-01 The purpose of this study is to identify an optimal weight based dose of azathioprine that is safe and effective in the treatment of subjects with active Crohn's disease requiring treatment with corticosteroids, and for maintaining remission in those subjects.
NCT00109473 Trial of Growth Hormone Therapy in Pediatric Crohn's Disease Completed Genentech, Inc. Phase 2 2005-04-01 The purpose of this study is to determine whether taking a growth hormone (GH) drug called somatropin causes the intestine of a person with Crohn's Disease (CD) to heal faster when compared to a person with Crohn's Disease that does not receive growth hormone drug.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Mesalamine

Condition Name

Condition Name for Mesalamine
Intervention Trials
Ulcerative Colitis 35
Healthy 9
Crohn's Disease 5
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Condition MeSH

Condition MeSH for Mesalamine
Intervention Trials
Colitis, Ulcerative 42
Colitis 42
Ulcer 41
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Clinical Trial Locations for Mesalamine

Trials by Country

Trials by Country for Mesalamine
Location Trials
United States 381
Canada 27
India 25
Poland 18
Italy 11
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Trials by US State

Trials by US State for Mesalamine
Location Trials
Florida 20
California 20
Texas 19
Michigan 16
Maryland 15
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Clinical Trial Progress for Mesalamine

Clinical Trial Phase

Clinical Trial Phase for Mesalamine
Clinical Trial Phase Trials
Phase 4 11
Phase 3 24
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Mesalamine
Clinical Trial Phase Trials
Completed 41
Recruiting 15
Terminated 10
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Clinical Trial Sponsors for Mesalamine

Sponsor Name

Sponsor Name for Mesalamine
Sponsor Trials
Shire 9
Valeant Pharmaceuticals International, Inc. 8
Ferring Pharmaceuticals 4
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Sponsor Type

Sponsor Type for Mesalamine
Sponsor Trials
Industry 58
Other 49
NIH 5
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Serving leading biopharmaceutical companies globally:

Express Scripts
McKinsey
Moodys
Boehringer Ingelheim
Mallinckrodt
Merck

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