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CLINICAL TRIALS PROFILE FOR MALARONE PEDIATRIC
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All Clinical Trials for Malarone Pediatric
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00421473 | Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients | Completed | Radboud University | Phase 4 | 2007-03-01 | Malarone® (atovaquone/proguanil) is frequently used in malaria prophylaxis. Unfortunately, there are indications that certain anti-HIV agents may decrease atovaquone plasma levels by induction of atovaquone metabolism. For travelling HIV patients, the clinical consequences of these possible drug drug interactions are serious, since a diminished exposure to the anti-malarial drug will result in suboptimal prophylaxis of malaria and potential development of drug resistant strains of Plasmodium falciparum. The purpose of this study is to find out if HIV patients using HAART regimes with either lopinavir/ritonavir, atazanavir/ritonavir or efavirenz have lower atovaquone plasma levels than healthy volunteers after a single dose of atovaquone/proguanil. |
NCT00444106 | Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function | Completed | Novartis | Phase 4 | 2007-05-01 | To evaluate the potential effects of artemether- lumefantrine on the auditory function |
NCT00984256 | Weekly Dosing of Malarone ® for Prevention of Malaria | Completed | U.S. Army Medical Research and Materiel Command | Phase 2 | 2009-09-01 | The purpose of this study is to determine whether Malarone ®, which is a drug approved to prevent malaria when taken daily, will still effectively prevent malaria if taken weekly. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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