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CLINICAL TRIALS PROFILE FOR LOPINAVIR AND RITONAVIR

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Clinical Trials for Lopinavir And Ritonavir

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00004578	ABT-378/Ritonavir in Combination With Reverse Transcriptase Inhibitors in Antiretroviral Naïve HIV-Infected Subjects	Completed	Abbott	Phase 1/Phase 2	To assess the safety, tolerability and antiviral activity of lopinavir/ritonavir when administered orally in antiretroviral-HIV-1 infected subjects.
NCT00006144	A Study of HIV-Disease Development in Aging	Completed	National Institute of Allergy and Infectious Diseases (NIAID)	Phase 2	The purpose of this study is to better understand the relationship between age and HIV disease progression. This study will explore the possible relationship between age and HIV disease progression. Older age is an important risk factor for faster disease development, but older people may respond better to combination drug therapy. This relationship needs to be understood better.
NCT00014937	Simplified Drug Regimens for HIV Patients in ACTG 388 or Patients Who Responded to A First Potent Combination Regimen	Completed	National Institute of Allergy and Infectious Diseases (NIAID)	N/A	ACTG 388 was a clinical trial that compared three- and four-drug anti-HIV drug regimens and demonstrated the effectiveness of a three-drug regimen. This study will compare the ability of two different three-drug anti-HIV drug regimens to reduce levels of HIV in the blood. The study will also evaluate whether patients discontinue the regimens because of drug side effects.
NCT00017992	Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV	Unknown status	Triangle Pharmaceuticals	Phase 2	The purpose of this study is to see if emtricitabine is safe in children infected with HIV and to determine the best dose.

Clinical Trial Conditions for Lopinavir And Ritonavir

Condition Name

Condition Name for Lopinavir And Ritonavir
Intervention	Trials
HIV Infections	134
HIV	33
HIV Infection	30
Tuberculosis	12

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Condition MeSH

Condition MeSH for Lopinavir And Ritonavir
Intervention	Trials
HIV Infections	187
Acquired Immunodeficiency Syndrome	40
Immunologic Deficiency Syndromes	25
Infection	23

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Clinical Trial Locations for Lopinavir And Ritonavir

Trials by Country

Trials by Country for Lopinavir And Ritonavir
Location	Trials
United States	707
Spain	75
Thailand	61
Canada	54
South Africa	47

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Trials by US State

Trials by US State for Lopinavir And Ritonavir
Location	Trials
California	57
New York	50
Florida	39
Texas	38
Illinois	37

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Clinical Trial Progress for Lopinavir And Ritonavir

Clinical Trial Phase

Clinical Trial Phase for Lopinavir And Ritonavir
Clinical Trial Phase	Trials
Phase 4	80
Phase 3	54
Phase 2/Phase 3	10

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Clinical Trial Status

Clinical Trial Status for Lopinavir And Ritonavir
Clinical Trial Phase	Trials
Completed	182
Terminated	24
Unknown status	21

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Clinical Trial Sponsors for Lopinavir And Ritonavir

Sponsor Name

Sponsor Name for Lopinavir And Ritonavir
Sponsor	Trials
Abbott	55
National Institute of Allergy and Infectious Diseases (NIAID)	45
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	16

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Sponsor Type

Sponsor Type for Lopinavir And Ritonavir
Sponsor	Trials
Other	271
Industry	134
NIH	72

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