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Last Updated: December 12, 2024

CLINICAL TRIALS PROFILE FOR LONAFARNIB

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All Clinical Trials for Lonafarnib

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00003956 ↗	Combination Chemotherapy in Treating Patients With Advanced Cancer	Completed	National Cancer Institute (NCI)	Phase 1	1999-04-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of SCH 66336, fluorouracil, and leucovorin in treating patients who have advanced cancer.
NCT00003956 ↗	Combination Chemotherapy in Treating Patients With Advanced Cancer	Completed	Memorial Sloan Kettering Cancer Center	Phase 1	1999-04-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of SCH 66336, fluorouracil, and leucovorin in treating patients who have advanced cancer.
NCT00005030 ↗	SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver	Withdrawn	National Cancer Institute (NCI)	Phase 1	1999-09-29	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase I trial to compare the effectiveness of different doses of SCH 66336 before surgery in treating patients who have colorectal cancer that has metastasized to the liver.
NCT00005030 ↗	SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver	Withdrawn	M.D. Anderson Cancer Center	Phase 1	1999-09-29	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase I trial to compare the effectiveness of different doses of SCH 66336 before surgery in treating patients who have colorectal cancer that has metastasized to the liver.
NCT00006351 ↗	SCH 66336 Plus Gemcitabine in Treating Patients With Advanced Cancer of the Urinary Tract	Completed	European Organisation for Research and Treatment of Cancer - EORTC	Phase 2	2000-06-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining SCH 66336 and gemcitabine may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of SCH 66336 plus gemcitabine in treating patients who have advanced cancer of the urinary tract.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for Lonafarnib

Condition Name

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Condition Name for Lonafarnib
Intervention	Trials
Breast Cancer	4
Progeria	4
Hepatitis D	3
Chronic Delta Hepatitis	2
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Condition MeSH

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Condition MeSH for Lonafarnib
Intervention	Trials
Hepatitis D	10
Hepatitis	10
Hepatitis D, Chronic	7
Hepatitis A	5
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Clinical Trial Locations for Lonafarnib

Trials by Country

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Trials by Country for Lonafarnib
Location	Trials
United States	35
France	10
Germany	6
Turkey	4
Canada	3
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Trials by US State

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Trials by US State for Lonafarnib
Location	Trials
Texas	6
Maryland	5
Massachusetts	5
Illinois	2
California	2
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Clinical Trial Progress for Lonafarnib

Clinical Trial Phase

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Clinical Trial Phase for Lonafarnib
Clinical Trial Phase	Trials
Phase 3	4
Phase 2	17
Phase 1/Phase 2	2
[disabled in preview]	10
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Clinical Trial Status

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Clinical Trial Status for Lonafarnib
Clinical Trial Phase	Trials
Completed	15
Terminated	8
Withdrawn	4
[disabled in preview]	4
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Clinical Trial Sponsors for Lonafarnib

Sponsor Name

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Sponsor Name for Lonafarnib
Sponsor	Trials
Schering-Plough	8
Eiger BioPharmaceuticals	7
National Cancer Institute (NCI)	7
[disabled in preview]	11
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Sponsor Type

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Sponsor Type for Lonafarnib
Sponsor	Trials
Other	29
Industry	22
NIH	11
[disabled in preview]	0
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