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Last Updated: April 16, 2024

CLINICAL TRIALS PROFILE FOR IMATINIB MESYLATE


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All Clinical Trials for Imatinib Mesylate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed Medical Research Council Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed National Cancer Institute (NCI) Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00002514 ↗ Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission Completed Eastern Cooperative Oncology Group Phase 3 1993-04-01 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether stem cell transplantation is more effective than standard chemotherapy in treating acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is studying how well stem cell transplantation works compared to standard combination chemotherapy in treating patients with acute lymphoblastic leukemia in first remission.
NCT00004932 ↗ STI571 in Treating Patients With Recurrent Leukemia Completed National Cancer Institute (NCI) Phase 1 2002-01-01 RATIONALE: Imatinib mesylate may interfere with the growth of cancer cells and may be an effective treatment for leukemia. PURPOSE: Phase I trial to study the effectiveness of imatinib mesylate in treating patients who have recurrent leukemia.
NCT00004932 ↗ STI571 in Treating Patients With Recurrent Leukemia Completed Children's Oncology Group Phase 1 2002-01-01 RATIONALE: Imatinib mesylate may interfere with the growth of cancer cells and may be an effective treatment for leukemia. PURPOSE: Phase I trial to study the effectiveness of imatinib mesylate in treating patients who have recurrent leukemia.
NCT00006052 ↗ STI571 in Treating Patients With Accelerated Phase Chronic Myelogenous Leukemia Completed Novartis Phase 2 2000-06-01 RATIONALE: STI571 may interfere with the growth of cancer cells and may be effective treatment for chronic myelogenous leukemia. PURPOSE: Phase II trial to study the effectiveness of STI571 in treating patients who have accelerated phase chronic myelogenous leukemia.
NCT00006053 ↗ STI571 in Treating Patients With Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa Completed Novartis Phase 2 2000-06-01 RATIONALE: STI571 may interfere with the growth of cancer cells and may be effective treatment for chronic myelogenous leukemia. PURPOSE: Phase II trial to study the effectiveness of STI571 in treating patients who have chronic myeloid leukemia that has not responded to interferon alfa.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Imatinib Mesylate

Condition Name

Condition Name for Imatinib Mesylate
Intervention Trials
Leukemia 58
Gastrointestinal Stromal Tumor 23
Chronic Myeloid Leukemia 18
Gastrointestinal Stromal Tumors 14
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Condition MeSH

Condition MeSH for Imatinib Mesylate
Intervention Trials
Leukemia 137
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 105
Leukemia, Myeloid 101
Gastrointestinal Stromal Tumors 54
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Clinical Trial Locations for Imatinib Mesylate

Trials by Country

Trials by Country for Imatinib Mesylate
Location Trials
United States 962
Canada 73
Australia 53
Italy 48
United Kingdom 47
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Trials by US State

Trials by US State for Imatinib Mesylate
Location Trials
Texas 82
California 66
New York 55
Pennsylvania 46
Massachusetts 45
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Clinical Trial Progress for Imatinib Mesylate

Clinical Trial Phase

Clinical Trial Phase for Imatinib Mesylate
Clinical Trial Phase Trials
Phase 4 9
Phase 3 34
Phase 2/Phase 3 5
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Clinical Trial Status

Clinical Trial Status for Imatinib Mesylate
Clinical Trial Phase Trials
Completed 235
Terminated 58
Unknown status 25
[disabled in preview] 42
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Clinical Trial Sponsors for Imatinib Mesylate

Sponsor Name

Sponsor Name for Imatinib Mesylate
Sponsor Trials
National Cancer Institute (NCI) 111
Novartis Pharmaceuticals 52
Novartis 44
[disabled in preview] 71
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Sponsor Type

Sponsor Type for Imatinib Mesylate
Sponsor Trials
Other 340
Industry 174
NIH 116
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