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Last Updated: May 26, 2022

CLINICAL TRIALS PROFILE FOR GUANFACINE HYDROCHLORIDE


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All Clinical Trials for Guanfacine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004376 ↗ Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder Completed Yale University Phase 3 1994-09-01 OBJECTIVES: I. Evaluate the safety and efficacy of the alpha-2 adrenergic agonist guanfacine in children and adolescents with Tourette syndrome or other chronic tic disorder, and attention deficit hyperactivity disorder.
NCT00004376 ↗ Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder Completed National Center for Research Resources (NCRR) Phase 3 1994-09-01 OBJECTIVES: I. Evaluate the safety and efficacy of the alpha-2 adrenergic agonist guanfacine in children and adolescents with Tourette syndrome or other chronic tic disorder, and attention deficit hyperactivity disorder.
NCT00007592 ↗ Hypertension Screening and Treatment Program Completed US Department of Veterans Affairs 1989-06-01 Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00007592 ↗ Hypertension Screening and Treatment Program Completed VA Office of Research and Development 1989-06-01 Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00018603 ↗ Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD) Completed US Department of Veterans Affairs Phase 1 1999-11-01 This is a double-blind, placebo-controlled, randomized study lasting 8 weeks. Purpose of the study is two-fold: first, to use a pharmacological agent to treat symptoms of PTSD, and second, to explore neurobiological mechanisms of action of guanfacine.
NCT00018603 ↗ Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD) Completed VA Office of Research and Development Phase 1 1999-11-01 This is a double-blind, placebo-controlled, randomized study lasting 8 weeks. Purpose of the study is two-fold: first, to use a pharmacological agent to treat symptoms of PTSD, and second, to explore neurobiological mechanisms of action of guanfacine.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Guanfacine Hydrochloride

Condition Name

Condition Name for Guanfacine Hydrochloride
Intervention Trials
Attention Deficit Hyperactivity Disorder 7
Attention Deficit Disorder With Hyperactivity 5
ADHD 5
Attention-deficit/Hyperactivity Disorder 5
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Condition MeSH

Condition MeSH for Guanfacine Hydrochloride
Intervention Trials
Attention Deficit Disorder with Hyperactivity 24
Hyperkinesis 18
Disease 18
Hypertension 5
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Clinical Trial Locations for Guanfacine Hydrochloride

Trials by Country

Trials by Country for Guanfacine Hydrochloride
Location Trials
United States 233
United Kingdom 13
Spain 13
Germany 11
France 10
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Trials by US State

Trials by US State for Guanfacine Hydrochloride
Location Trials
Connecticut 19
New York 15
California 13
Tennessee 11
Texas 10
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Clinical Trial Progress for Guanfacine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Guanfacine Hydrochloride
Clinical Trial Phase Trials
Phase 4 20
Phase 3 12
Phase 2 17
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Clinical Trial Status

Clinical Trial Status for Guanfacine Hydrochloride
Clinical Trial Phase Trials
Completed 43
Recruiting 10
Active, not recruiting 3
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Clinical Trial Sponsors for Guanfacine Hydrochloride

Sponsor Name

Sponsor Name for Guanfacine Hydrochloride
Sponsor Trials
Shire 22
Yale University 17
National Institute on Drug Abuse (NIDA) 11
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Sponsor Type

Sponsor Type for Guanfacine Hydrochloride
Sponsor Trials
Other 73
Industry 26
NIH 24
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