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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR CARPROFEN


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All Clinical Trials for Carprofen

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02017197 ↗ Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil Completed Fundação de Amparo à Pesquisa do Estado de São Paulo Phase 4 2014-08-01 The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT02017197 ↗ Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil Completed Federal University of São Paulo Phase 4 2014-08-01 The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT03911336 ↗ Harnessing Chronomodulation to Enhance Osteogenesis Suspended Osteology Foundation Phase 4 2023-01-01 Chronotherapy is an emerging field in biomedicine that leverages on fine-tuning the timing of drug delivery to obtain a therapeutic effect. Dr. Tamimi and his team have successfully harnessed chronotherapy using NSAIDs to enhance bone healing in a murine fracture model. Unpublished findings revealed that mice receiving carprofen for 3 days post-fracture exclusively during activity hours exhibited superior bone healing outcomes in comparison to specimens that received the same drug during resting hours. This is a 3-arm RCT aimed at evaluating the effect of different chronotherapeutic NSAID regimens on intraoral bone healing in humans using an extraction socket healing model in the context of an early implant placement protocol. The primary aim is to elucidate whether there are differences in osteogenesis and in the characteristics of the newly formed bone between patients following different post-operative NSAID chronotherapeutic protocols. Secondary endpoints of interest include assessment of alveolar bone and soft tissue dimensional changes between pre- and post-extraction, implant insertion torque, serum CRP levels, wound healing index and patient-reported discomfort at different time points. If proven beneficial, the proposed chronotherapeutic approach could be readily implemented in clinical practice as a standalone therapy or as a valuable complement to existing standard-of-care protocols, due to its simplicity, safety and cost-effectiveness.
NCT03911336 ↗ Harnessing Chronomodulation to Enhance Osteogenesis Suspended Gustavo Avila-Ortiz DDS, MS, PhD Phase 4 2023-01-01 Chronotherapy is an emerging field in biomedicine that leverages on fine-tuning the timing of drug delivery to obtain a therapeutic effect. Dr. Tamimi and his team have successfully harnessed chronotherapy using NSAIDs to enhance bone healing in a murine fracture model. Unpublished findings revealed that mice receiving carprofen for 3 days post-fracture exclusively during activity hours exhibited superior bone healing outcomes in comparison to specimens that received the same drug during resting hours. This is a 3-arm RCT aimed at evaluating the effect of different chronotherapeutic NSAID regimens on intraoral bone healing in humans using an extraction socket healing model in the context of an early implant placement protocol. The primary aim is to elucidate whether there are differences in osteogenesis and in the characteristics of the newly formed bone between patients following different post-operative NSAID chronotherapeutic protocols. Secondary endpoints of interest include assessment of alveolar bone and soft tissue dimensional changes between pre- and post-extraction, implant insertion torque, serum CRP levels, wound healing index and patient-reported discomfort at different time points. If proven beneficial, the proposed chronotherapeutic approach could be readily implemented in clinical practice as a standalone therapy or as a valuable complement to existing standard-of-care protocols, due to its simplicity, safety and cost-effectiveness.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Carprofen

Condition Name

Condition Name for Carprofen
Intervention Trials
Atrial Fibrillation 1
Tooth Loss 1
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Condition MeSH

Condition MeSH for Carprofen
Intervention Trials
Tooth Loss 1
Atrial Fibrillation 1
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Clinical Trial Locations for Carprofen

Trials by Country

Trials by Country for Carprofen
Location Trials
Brazil 1
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Clinical Trial Progress for Carprofen

Clinical Trial Phase

Clinical Trial Phase for Carprofen
Clinical Trial Phase Trials
Phase 4 2
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Clinical Trial Status

Clinical Trial Status for Carprofen
Clinical Trial Phase Trials
Completed 1
Suspended 1
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Clinical Trial Sponsors for Carprofen

Sponsor Name

Sponsor Name for Carprofen
Sponsor Trials
Fundação de Amparo à Pesquisa do Estado de São Paulo 1
Federal University of São Paulo 1
Osteology Foundation 1
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Sponsor Type

Sponsor Type for Carprofen
Sponsor Trials
Other 5
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