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Last Updated: April 16, 2024

CLINICAL TRIALS PROFILE FOR CAMPTOSAR


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505(b)(2) Clinical Trials for Camptosar

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
New Combination NCT00177853 ↗ Celecoxib, Irinotecan and Concurrent Radiotherapy in Preoperative Pancreatic Cancer Terminated Pharmacia and Upjohn Phase 1 2006-12-01 The purposes of this study are to examine the effects of a new combination of drugs, celecoxib (Celebrex®) and irinotecan (CPT-11), with standard radiation therapy on people before they undergo surgery; to determine what effects this combination has on pancreatic cancer; and to determine the highest dose of celecoxib and irinotecan that can be given safely without causing severe side effects. While not an endpoint, it is hoped that this combination will also shrink tumors enough for excision.
New Combination NCT00177853 ↗ Celecoxib, Irinotecan and Concurrent Radiotherapy in Preoperative Pancreatic Cancer Terminated University of Pittsburgh Phase 1 2006-12-01 The purposes of this study are to examine the effects of a new combination of drugs, celecoxib (Celebrex®) and irinotecan (CPT-11), with standard radiation therapy on people before they undergo surgery; to determine what effects this combination has on pancreatic cancer; and to determine the highest dose of celecoxib and irinotecan that can be given safely without causing severe side effects. While not an endpoint, it is hoped that this combination will also shrink tumors enough for excision.
New Combination NCT00215982 ↗ Study of Capecitabine With Irinotecan and Oxaliplatin (Eloxatin) in Advanced Colorectal Cancer Completed Roche Pharma AG Phase 2 2004-12-01 The purpose of this study is to find out how effective the new combination of the drugs Capecitabine (Xeloda), Oxaliplatin (Eloxatin), and Irinotecan (Camptosar) are against colon and rectal cancer. All three of these drugs are approved by the Food and Drug Administration (FDA) for the treatment of colon or rectal cancer. This however is the first time that these three drugs have been combined in this schedule for the treatment of colon/rectal cancer.
New Combination NCT00215982 ↗ Study of Capecitabine With Irinotecan and Oxaliplatin (Eloxatin) in Advanced Colorectal Cancer Completed H. Lee Moffitt Cancer Center and Research Institute Phase 2 2004-12-01 The purpose of this study is to find out how effective the new combination of the drugs Capecitabine (Xeloda), Oxaliplatin (Eloxatin), and Irinotecan (Camptosar) are against colon and rectal cancer. All three of these drugs are approved by the Food and Drug Administration (FDA) for the treatment of colon or rectal cancer. This however is the first time that these three drugs have been combined in this schedule for the treatment of colon/rectal cancer.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Camptosar

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003970 ↗ Genetic Testing Plus Irinotecan in Treating Patients With Solid Tumors or Lymphoma Completed National Cancer Institute (NCI) Phase 1 1999-01-01 Phase I trial to study genetic testing and the effectiveness of irinotecan in treating patients who have solid tumors and lymphoma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Genetic testing for a specific enzyme may help doctors determine whether side effects from or response to chemotherapy are related to a person's genetic makeup
NCT00004078 ↗ Irinotecan in Treating Children With Refractory Solid Tumors Completed National Cancer Institute (NCI) Phase 2 1999-10-01 This phase II trial is studying irinotecan to see how well it works in treating children with refractory solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00004078 ↗ Irinotecan in Treating Children With Refractory Solid Tumors Completed Children's Oncology Group Phase 2 1999-10-01 This phase II trial is studying irinotecan to see how well it works in treating children with refractory solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00004103 ↗ Combination Chemotherapy Followed by Surgery in Treating Patients With Stomach Cancer Completed National Cancer Institute (NCI) Phase 2 1998-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with surgery may kill more tumor cells. PURPOSE: This phase II trial is studying how well irinotecan and cisplatin followed by surgery, floxuridine, and cisplatin work in treating patients with stomach cancer.
NCT00004103 ↗ Combination Chemotherapy Followed by Surgery in Treating Patients With Stomach Cancer Completed New York University School of Medicine Phase 2 1998-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with surgery may kill more tumor cells. PURPOSE: This phase II trial is studying how well irinotecan and cisplatin followed by surgery, floxuridine, and cisplatin work in treating patients with stomach cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Camptosar

Condition Name

Condition Name for Camptosar
Intervention Trials
Colorectal Cancer 20
Recurrent Colon Cancer 14
Recurrent Rectal Cancer 14
Unspecified Adult Solid Tumor, Protocol Specific 11
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Condition MeSH

Condition MeSH for Camptosar
Intervention Trials
Colorectal Neoplasms 54
Adenocarcinoma 50
Neoplasms 38
Pancreatic Neoplasms 34
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Clinical Trial Locations for Camptosar

Trials by Country

Trials by Country for Camptosar
Location Trials
Canada 88
Australia 42
United Kingdom 23
Japan 19
Spain 17
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Trials by US State

Trials by US State for Camptosar
Location Trials
California 66
Texas 49
New York 48
Pennsylvania 43
Illinois 43
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Clinical Trial Progress for Camptosar

Clinical Trial Phase

Clinical Trial Phase for Camptosar
Clinical Trial Phase Trials
Phase 4 1
Phase 3 15
Phase 2 95
[disabled in preview] 97
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Clinical Trial Status

Clinical Trial Status for Camptosar
Clinical Trial Phase Trials
Completed 104
Terminated 38
Recruiting 28
[disabled in preview] 31
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Clinical Trial Sponsors for Camptosar

Sponsor Name

Sponsor Name for Camptosar
Sponsor Trials
National Cancer Institute (NCI) 92
Genentech, Inc. 12
M.D. Anderson Cancer Center 10
[disabled in preview] 15
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Sponsor Type

Sponsor Type for Camptosar
Sponsor Trials
Other 189
Industry 120
NIH 93
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