The purpose of this study is to determine whether different types of antidepressant medicines
relieve back pain that has lasted at least six months on a daily basis. Study participants
will be assigned to treatment with either a antidepressant acting on the serotonin system in
the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control
medication not expected to relieve pain (benztropine). Each participant will be seen at least
nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.
The purpose of this study is to determine whether different types of antidepressant medicines
relieve back pain that has lasted at least six months on a daily basis. Study participants
will be assigned to treatment with either a antidepressant acting on the serotonin system in
the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control
medication not expected to relieve pain (benztropine). Each participant will be seen at least
nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
Completed
AstraZeneca
Phase 4
2006-05-01
In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M.
Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to
be an effective treatment. However, since it is an intramuscular injection, it is more
complicated and perhaps less acceptable to patients as well as more likely to cause EPS
(extrapyramidal symptoms). Of late in our emergency room, we started using high dose
Quetiapine 300 mg PO to replace the "cocktail" for treating agitation. It has shown promising
results.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.