Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy
Not yet recruiting
Jianxing He
N/A
2022-08-01
Cough after lobectomy is common. The prevention and treatment of cough after lobectomy is not
standardized. Breztri Aerosphere is often used to relieve cough. Therefore, we conduct a
single center placebo-controlled study to evaluate the efficacy and safety of perioperative
use of Breztri Aerosphere in relieving cough after lobectomy.
Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian Patients With Chronic Obstructive Pulmonary Disease
NOT_YET_RECRUITING
AstraZeneca
PHASE4
2025-10-30
The purpose of this study is to observe the safety and tolerability of Breztri aerosphereTM as maintenance treatment in Indian patients with moderate to severe COPD.
Bronchodilators and Lung Mechanics During Exercise in COPD
RECRUITING
Dr. J. Alberto Neder
PHASE4
2024-11-10
Bronchodilators are medications that open the bronchi to help patients with COPD to breathe better. It is still not known exactly how this effect improves shortness of breath in people with COPD. The goal of this clinical trial is to determine whether bronchodilators lower resistance in the smallest airways in the lungs, and whether this will improve the feeling of breathlessness in these patients.
The main questions the investigators attempt to answer are:
* In patients with COPD, does treatment with a short-acting bronchodilator improve small airway resistance during exercise?
* In patients with COPD, does acute treatment with short-acting bronchodilator improve breathlessness and exercise endurance?
The investigators will compare short-acting bronchodilators to placebo (a substance that contains no drug) to see if the bronchodilator medications improve small airway resistance and breathlessness during exercise.
Participants will:
* Visit the research laboratory 3 visits to complete tests of lung function and exercise
* Complete 2 identical visits (Visit 2 and 3), one in which the participant receives bronchodilator and one in which the participant receives placebo.
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