A Non-Blinded Study Demonstrating the Effectiveness and Safety of Azilect Alone or in Combination Therapy in Parkinson's Disease
Teva Neuroscience, Inc.
Patients with Parkinson's Disease (PD) will be divided into 2 groups at each study center at
their first visit based on the drugs they are taking for their PD:
- Group 1 Patients using Azilect and no other therapy.
- Group 2 Azilect in combination with other medications like Levodopa, Mirapex, or
The Effects of Rasagiline on Cognitive Deficits Associated With Parkinson's Disease
The objective of the study is to assess the effects of rasagiline on cognitive functions in
patient with Parkinson's disease. Patients on any dopaminergic medications will be assigned
to receive rasagiline 1 mg or placebo over 3 months. Cognitive functions will be assessed by
selected neuropsychological tests representing each cognitive domain.
To identify the occurrence of serotonin toxicity in Parkinson's Disease (PD) patients
receiving antidepressant therapy and rasagiline, compared to those receiving rasagiline
without antidepressant medications and compared to PD patients receiving antidepressants,
but not rasagiline.
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