Clinical Evaluation of the Photoallergy Potential of Atralin Gel
Completed
Coria Laboratories, Ltd.
Phase 1
2008-01-01
To assess the potential of tretinoin gel 0.05% and its vehicle to produce photoallergic
reactions, measured as skin reactions following induction and challenge.
Study to Determine the Phototoxity of Atralin (Tretinoin) Gel, 0.05%
Completed
Coria Laboratories, Ltd.
Phase 1
2008-01-01
To assess the potential of tretnoin gel 0.05% to produce phototoxic reactions, measured as
skin reactions 24 and 48 hours after UV radiation of drug on skin.
Erythematotelangiectatic rosacea is a type of rosacea that causes a red face often with
frequent flushing, topical sensitivity and prominent blood vessels. We think that long term
damage to skin from the sun (photodamage) may play a role in causing this type of rosacea.
Tretinoin is a topical medication that is known to improve photodamage. We want to find out
if Atralin (tretinoin 0.05%) Gel used for up to 46 weeks will improve
erythematotelangiectatic rosacea (ETR).
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