Patent: 9,714,422
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Summary for Patent: 9,714,422
| Title: | Reducing intron retention |
| Abstract: | Disclosed herein are methods, compositions, polynucleic acid polymers, assays, and kits for inducing processing of a partially processed mRNA transcript to remove a retained intron to produce a fully processed mRNA transcript that encodes a full-length functional form of a protein. Also described herein are methods and compositions for treating a disease or condition characterized by impaired production of a full-length functional form of a protein or for treating a disease or condition characterized by a defective splicing in a subject. |
| Inventor(s): | Vorechovsky; Igor (Southampton, GB), Kralovicova; Jana (Southampton, GB) |
| Assignee: | UNIVERSITY OF SOUTHAMPTON (Southampton, Hampshire, GB) |
| Application Number: | 15/148,303 |
| Patent Claims: | see list of patent claims |
Details for Patent 9,714,422
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2034-06-16 |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2034-06-16 | |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2034-06-16 | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
