Patent: 9,221,882
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Summary for Patent: 9,221,882
Title: | Biosynthetic proline/alanine random coil polypeptides and their uses |
Abstract: | We discovered that a biosynthetic polypeptide, consisting of at least about 50 proline (Pro) and alanine (Ala) amino acid residues, forms a random coil, and increases the stability of other compounds to which it is conjugated, such as small molecules and polypeptides. We describe such biosynthetic polypeptides, constructs containing such polypeptides, ways of making them, and their use. |
Inventor(s): | Skerra; Arne (Freising, DE), Binder; Uli (Freising, DE), Schlapschy; Martin (Freising, DE) |
Assignee: | Technische Universitat Munchen (Munich, DE) XL-Protein GmbH (Freising, DE) |
Application Number: | 13/697,569 |
Patent Claims: | see list of patent claims |
Details for Patent 9,221,882
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 05/05/2004 | ⤷ Try a Trial | 2030-05-21 |
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 12/02/2004 | ⤷ Try a Trial | 2030-05-21 |
Amphastar Pharmaceuticals, Inc. | AMPHADASE | hyaluronidase | Injection | 021665 | 10/26/2004 | ⤷ Try a Trial | 2030-05-21 |
Akorn, Inc. | HYDASE | hyaluronidase | Injection | 021716 | 10/25/2005 | ⤷ Try a Trial | 2030-05-21 |
Chiesi Usa, Inc. | RETAVASE | reteplase | For Injection | 103786 | 10/30/1996 | ⤷ Try a Trial | 2030-05-21 |
Swedish Orphan Biovitrum Ab (publ) | KINERET | anakinra | Injection | 103950 | 11/14/2001 | ⤷ Try a Trial | 2030-05-21 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |