Patent: 8,987,242
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Summary for Patent: 8,987,242
Title: | Morpholinone compounds as factor IXA inhibitors |
Abstract: | The present invention provides a compound of Formula (I) ##STR00001## as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes. |
Inventor(s): | Chackalamannil; Samuel (Califon, NJ), Chan; Tin-Yau (Edison, NJ), Chelliah; Mariappan V. (Edison, NJ), Clasby; Martin C. (Plainsboro, NJ), Dwyer; Michael (Scotch Plains, NJ), Greenlee; William J. (Teaneck, NJ), Hirabayashi; Tomokazu (Shinjuku-ku, JP), Neelamkavil; Santhosh (Scotch Plains, NJ), Nishida; Hidemitsu (Shinjuku-ku, JP), Saitoh; Fumihiko (Shinjuku-ku, JP), Shah; Unmesh (Green Brook, NJ), Xia; Yan (Edison, NJ) |
Assignee: | Merck Sharp & Dohme Corp. (Rahway, NJ) Mochida Pharmaceuticals Co., Ltd. (Tokyo, JP) |
Application Number: | 12/791,464 |
Patent Claims: | see list of patent claims |
Details for Patent 8,987,242
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bayer Healthcare Pharmaceuticals Inc. | TRASYLOL | aprotinin | Injection | 020304 | 12/29/1993 | ⤷ Try a Trial | 2028-12-05 |
Microbix Biosystems Inc. | KINLYTIC | urokinase | For Injection | 021846 | 01/16/1978 | ⤷ Try a Trial | 2028-12-05 |
Genentech, Inc. | TNKASE | tenecteplase | For Injection | 103909 | 06/02/2000 | ⤷ Try a Trial | 2028-12-05 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |