Patent: 8,877,710
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Summary for Patent: 8,877,710
Title: | Methods of identifying critically ill patients at increased risk of development of organ failure and compounds for the treatment hereof |
Abstract: | The present invention relates to compounds for treatment that protects the endothelium, prevent pathologic thrombus formation in the microcirculation and preserve platelet number and function and thus may be related to minimizing or preventing development of organ failure, including multiple organ failure (MOF), and, hence, death in critically ill patients by administration of agent(s) limiting the platelets ability to aggregate and form clots and/or by agents modulating/preserving endothelial integrity and/or by agent(s) increasing the rate of thrombus lysis, and Another aspect of the invention related to by a cell-based whole blood viscoelastical haemostatic assay identifying critically ill patients at increased risk of development of organ failure, including multiple organ failure (MOF) and death. |
Inventor(s): | Johansson; Par (Dosjebro, SE), Ostrowski; Sisse Rye (Hellerup, DK) |
Assignee: | Righospitalet (Kobenhavn O, DK) |
Application Number: | 13/142,935 |
Patent Claims: | see list of patent claims |
Details for Patent 8,877,710
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Janssen Biotech, Inc. | REOPRO | abciximab | Injection | 103575 | 12/22/1994 | ⤷ Try a Trial | 2028-12-30 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |