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Last Updated: March 29, 2024

Patent: 8,440,445


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Summary for Patent: 8,440,445
Title:Neutral protease (NP) and product by using neutral protease for tissue dissociation as well as method for the production thereof
Abstract: The use of a neutral protease (NP) together with a collagenase consists in that a neutral protease which is not contained in a collagenase enzyme preparation and which is not produced by a recombinant production ia mixed before the beginning of a tissue dissociation with a collagenase or a collagenase enzyme preparation with an individual dosage of the quantitative proportions of neutral protease and collagenase for improving the isolation results with respect to yield, viability and integrity of the cells.
Inventor(s): Kurfurst; Manfred (Moorrege, DE), Raemsch; Christian (Uetersen, DE), Raemsch-Guenther; Nicole (Uetersen, DE), Friedrich; Olaf (Tornesch, DE), Huettler; Silke (Uetersen, DE), Brandhorst; Daniel (Linden, DE), Berney; Thierry (Arenthon, FR), Bucher; Pascal (Geneva, CH), Brandhorst; Heide (Linden, DE)
Assignee: Nordmark Arzneimittel GmbH & Co. KG (Uetersen, DE)
Application Number:10/869,313
Patent Claims:see list of patent claims

Details for Patent 8,440,445

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 ⤷  Try a Trial 2023-07-09
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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