Patent: 7,763,451
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Summary for Patent: 7,763,451
Title: | Methods for preparing Bacillus anthracis protective antigen for use in vaccines |
Abstract: | The invention relates to improved methods of producing and recovering B. anthracis protective antigen (PA), especially modified PA which is protease resistant, and to methods of using of these PAs or nucleic acids encoding these PAs for eliciting an immunogenic response in humans, including responses which provide protection against, or reduce the severity of, B. anthracis bacterial infections and which are useful to prevent and/or treat illnesses caused by B. anthracis, such as inhalation anthrax, cutaneous anthrax and gastrointestinal anthrax. |
Inventor(s): | Shiloach; Joseph (Rockville, MD), Leppla; Stephen H. (Bethesda, MD), Ramirez; Delia M. (Bethesda, MD), Schneerson; Rachel (Bethesda, MD), Robbins; John B. (Chevy Chase, MD), Hsu; S. Dana (Bethesda, MD), Rosovitz; Mary Jo (Germantown, MD) |
Assignee: | The United States of America as represented by the Department of Health and Human Services (Washington, DC) N/A (N/A) |
Application Number: | 10/290,712 |
Patent Claims: | see list of patent claims |
Details for Patent 7,763,451
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Emergent Biodefense Operations Lansing Llc | BIOTHRAX | anthrax vaccine adsorbed | Injection | 103821 | 11/12/1998 | ⤷ Try a Trial | 2021-11-09 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |