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Last Updated: April 23, 2024

Patent: 6,590,078


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Summary for Patent: 6,590,078
Title: DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
Abstract:The invention includes novel fusion nucleic acids encoding fusion polypeptides which when expressed in a filamentous fungus result in the expression of fusion polypeptides. The fusion nucleic acids comprise four nucleic acids which encode a fusion polypeptide comprising first, second, third and fourth amino acid sequences. The first nucleic acid encodes a signal polypeptide functional as a secretory sequence in a first filamentous fungus. The second nucleic acid encodes a secreted polypeptide or functional portion thereof which is normally secreted from the same filamentous fungus or a second filamentous fungus. The third nucleic acid encodes a cleavable linker while the fourth nucleic acid comprises at least two nucleic acids encoding desired polypeptides.
Inventor(s): Ward; Michael (San Francisco, CA), Power; Scott D. (San Bruno, CA)
Assignee: Genencor International, Inc. (Palo Alto, CA)
Application Number:09/912,733
Patent Claims:see list of patent claims

Details for Patent 6,590,078

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 ⤷  Try a Trial 2017-01-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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